Synlett 2017; 28(17): 2262-2266
DOI: 10.1055/s-0036-1590820
letter
© Georg Thieme Verlag Stuttgart · New York

Synthesis of Unsymmetrical Aza[7]helicenes by One-Pot Wittig–Heck and Photodehydrogenation Sequence

Blessy Rajan, Ashutosh V. Bedekar*
  • Department of Chemistry, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara 390 002, India   Email: avbedekar@yahoo.co.in
Grant received from Science and Engineering Research Board (SERB), New Delhi No. SR/S1/OC-74/2012.
Further Information

Publication History

Received: 29 April 2017

Accepted after revision: 06 June 2017

Publication Date:
14 July 2017 (eFirst)

We dedicate this paper to Professor Pradeep Kumar of National Chemical Laboratory (Pune, India) on the occasion of his 60th birthday

Abstract

An efficient protocol for the synthesis of unsymmetrical aza[7]helicenes has been developed. The bis-styryl-type substrates for regiospecific photodehydrogenative oxidative double cyclization to give helicenes were prepared by a one-pot Wittig–Heck sequence as well as a stepwise procedure. The derivatives were characterized by single-crystal X-ray diffraction analysis and fluorescence spectroscopy.

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