Rhodium-Catalyzed C–C Bond Olefination of Ring-Fused Benzocyclobutenols and Application in the Construction of Polycyclic CompoundsC.Z. is grateful for financial support from Soochow University, the National Natural Science Foundation of China (Grant no. 21402134), the Natural Science Foundation of Jiangsu Province (Grant no. BK20140306), and the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD).
Received: 25 May 2017
Accepted after revision: 14 June 2017
14 July 2017 (eFirst)
Published as part of the Cluster C–C Activation
A novel rhodium-catalyzed C–C bond olefination of ring-fused benzocyclobutenols with ethyl acrylate is described. A variety of versatile olefinated products were efficiently generated at room temperature and then readily converted into many useful polycyclic compounds by one-step processes. The reaction provides a practical C–C bond olefination method with high atom efficiency.