Synlett
DOI: 10.1055/s-0036-1590906
letter
© Georg Thieme Verlag Stuttgart · New York

A Convenient Method for the Synthesis of Imidazo[1,2-a]pyridines with a New Approach

Saeed Balalaie*a, b, Fatemeh Derakhshan-Panaha, c, Mohammad Ali Zolfigol*c, Frank Romingerd
  • aPeptide Chemistry Research Center, K.N. Toosi University of Technology, P.O. Box 15875-4416, Tehran, Iran   Email: balalaie@kntu.ac.ir
  • bMedical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran
  • cDepartment of Organic Chemistry, Faculty of Chemistry, Bu-Ali Sina University, Hamedan, Iran   Email: zolfi@basu.ac.ir   Email: mzolfigol@yahoo.com
  • dOrganisch-Chemisches Institut der Universität Heidelberg, Im Neuenheimer Feld 270, 69120 Heidelberg, Germany
We are grateful to the Iran National Science Foundation (INSF, Grant No. 96003234) for financial support.
Further Information

Publication History

Received: 05 July 2017

Accepted after revision: 19 August 2017

Publication Date:
05 September 2017 (eFirst)

Dedicated to Prof. Gebhard Haberhauer on the occasion of his birthday

Abstract

A new approach for the efficient synthesis of imidazo[1,2-a]pyridines is described. The synthesis was carried out via the reaction of functionalized 2-aminopyridine that were formed through a three-component reaction and phenacyl bromide derivatives.

Supporting Information