Reference Ranges of Fetal Cerebral Lateral Ventricle Parameters by Ultrasonography

Abstract

Objectives This study was done to evaluate the normal fetal cerebral lateral ventricle dimensions with transabdominal ultrasonography. The atrial width (AW), ventricle-to-choroid measurement (V-C), ventricle-to-hemisphere ratio (VHR), and combined anterior horn measurement (CAHM) were taken.

Methods This was a cross-sectional study involving 400 normal singleton pregnant subjects whose gestational ages were between 14 and 40 weeks. Transabdominal sonography was performed to obtain the values of the fetal cerebral lateral ventricle (FCLV) parameters. Data were reported as mean ± standard deviation (SD) for continuous variables. The degrees of correlation between FCLV parameters and the estimated gestational age (EGA) were obtained using Pearson's correlation. Regression equations were used to generate the reference limits for the FCLV measurements.

Results The values of AW, V-C measurements and CAHM increased with advancing gestation. The mean values of the AW, V-C and CAHM from 14 to 40 weeks increased from 6.60 ± 0.94 mm to 9.75 ± 0.07 mm (R² = 0.114), 0.80 ± 0.00 mm to 1.90 ± 0.14 mm (R² = 0.266), and 6.95 ± 0.06 mm to 23.07 ± 4.02 mm (R² = 0.692) respectively, while the mean VHR decreased from 61.20 ± 1.60% to 42.84 ± 2.91% (R² = 0.706) over the same period.

Conclusion The AW, V-C, and CAHM increase, while VHR decreases with advancing gestation.

Resumo

Objetivos O presente estudo objetiva avaliar as dimensões do ventrículo lateral de cérebros fetais por meio de ultrassonografia transabdominal. Foram medidos a largura do átrio (LA), a medida do ventrículo ao coroide (V-C), a razão ventrículo/ hemisfério (RVH), e a medida dos cornos anteriores combinados (CAC).

Métodos Estudo transversal com 400 grávidas de único feto com idades gestacionais entre 14 e 40 semanas. Sonografias transabdominais foram realizadas para obter os valores dos parâmetros do ventrículo lateral de cérebros fetais (VLCF). Dados foram apresentados em média ± desvio padrão para variáveis contínuas. Os graus de correlação entre parâmetros de VLCF e idade gestacional estimada foram obtidos usando a correlação de Pearson. Equações de regressão foram usadas para gerar as referências-limite para medidas de VLCF.

Resultados Os valores de LA, medida do V-C e CAC aumentaram com o avanço da gestação. Os valores médios de LA, V-C e CAC de 14 a 40 semanas aumentaram de 6,60 ± 0,94 mm a 9,75 ± 0,07 mm (R² = 0,114), de 0,80 ± 0,00 mm a 1,90 ± 0,14 mm (R² = 0,266), e de 6,95 ± 0,06 mm a 23,07 ± 4,02 mm (R² = 0,692), respectivamente, enquanto a RVH média diminuiu de 61,20 ± 1,60% para 42,84 ± 2,91% (R² = 0,706) no mesmo período.

Conclusão A LA, V-C, e CAC aumentaram, enquanto a RVH diminuiu com o avanço da gestação.

Keywords

ultrasonography - fetus - ventricle - ventriculomegaly - reference range

Palavras-chave

ultrassonografia - feto - ventrículo - ventriculomegalia - intervalo de referência

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