Abstract
Subclinical hypothyroidism has been found to be associated with adverse reproductive
outcomes, such as infertility, miscarriage, preterm birth, and complications of pregnancy.
Multiple studies have investigated the relationships between thyroid function, thyroid
antibodies, fertility, and pregnancy. Thyroid autoimmunity is the most common cause
of hypothyroidism in iodine-sufficient locations. Thyroid antibodies have been associated
with adverse reproductive outcomes such as miscarriage and infertility. Debate exists
regarding the method of identification of thyroid dysfunction in pregnancy, which
can be conducted by targeted screening or by universal screening. Multiple professional
societies have issued recommendations for the evaluation and treatment of thyroid
dysfunction and pregnancy.
Keywords
subclinical hypothyroidism - antithyroid antibodies - miscarriage - fertility - pregnancy