Die Rolle der Darm-Gehirn-Achse in der Pathophysiologie des Reizdarmsyndroms

Summary

Gehirn und Darm interagieren eng und wechselseitig miteinander, hierbei haben sich die Begriffe Gehirn-Darm-Achse, aber auch Darm-Gehirn-Achse durchgesetzt. Im Artikel werden entsprechende Veränderungen dieser Achse am Beispiel des Reizdarmsyndroms diskutiert. Abschließend werden therapeutische Ansätze, die die Darm-Gehirn-Achse beeinflussen, vorgestellt.

Keywords

Brain-Gut-Achse - CRF - endokrin - enterisches Nervensystem - Gastrointestinaltrakt - Hypothalamus - Mikrobiom-Darm-Gehirn-Achse - neuronal - Stress

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