Abstract
Introduction Acromegaly is a chronic disease caused by growth hormone (GH) excess due to a GH-secreting
pituitary adenoma in most cases. There is reasonable data to presume the possible
influence of chronic GH and insulin-like growth factor I (IGF-I) hyperproduction on
the anatomical structures involved in normal sound perception, and on its conductive
and/or sensorineural part.
Objectives To review the literature about acromegaly and hearing loss.
Data Synthesis A systematic literature search was performed using the MEDLINE database, including
hand-searching reference lists from original articles. The search was performed using
the terms hearing loss and acromegaly, and only 5 studies were found.
Conclusion The results are not consistent, but led to different conclusions. Therefore, more
studies with greater numbers of patients with acromegaly are needed.
Keywords
deafness - acromegaly - hearing loss
