Abstract
Uterine fibroids affect a wide cross-section of the population, with prevalence, symptom
severity, and overall disease burden generally higher among black women, likely due
to both genetic and environmental factors. Potential symptoms of uterine fibroids
include painful and excessive uterine bleeding, interference with everyday life and
self-image, and impaired fertility. Because of the high estimated prevalence and costs
associated with treatments, the direct and indirect costs of uterine fibroids are
substantial for both the health care system and the individual patient. Special patient
populations—such as black women, women seeking to retain fertility, and women with
asymptomatic fibroids—have particular treatment needs that require a variety of diagnostic
methods and treatment options. Despite the widespread occurrence of uterine fibroids
and newer treatment options, little high-quality data are available to formulate evidence-based
guidelines that address these unmet patient needs. Specific areas in need of attention
include improving diagnostic techniques, increasing patient access to early treatment,
and identifying best practices for this diverse patient population.
Keywords
uterine fibroids - disease burden - economic burden - unmet medical need - leiomyomas
