NHC-Catalyzed Synthesis of Benzazole-Phosphine Ligands under an Air Atmosphere

Abstract

An efficient strategy for the synthesis of benzazole-phosphine ligand precursors via N-heterocyclic carbene catalyzed aerobic oxidative cyclization reaction has been performed. The reaction displays broad functional group tolerance and high atom economy, and the transformation has been further applied to benzazole-phosphine ligand synthesis.

Key words

N-heterocyclic carbenes - oxidative cyclization - organcocatalysis - benzazoles phosphine ligand

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