Recent Developments in the Synthesis of Nitrogen-Containing Heterocycles through C–H/N–H Bond Functionalizations and Oxidative Cyclization

Xiang Liu; Yu Huang; Xu Meng; Jihui Li; Dong Wang; Yongxin Chen; Dong Tang; Baohua Chen

doi:10.1055/s-0037-1611476

Synlett, Inhaltsverzeichnis

Synlett 2019; 30(09): 1026-1036
DOI: 10.1055/s-0037-1611476

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Recent Developments in the Synthesis of Nitrogen-Containing Heterocycles through C–H/N–H Bond Functionalizations and Oxidative Cyclization

Authors

Xiang Liu *

^aCollege of Materials and Chemical Engineering, Key Laboratory of Inorganic Nonmetallic Crystalline and Energy Conversion Materials, China Three Gorges University, Yichang, Hubei 443002, P. R. of China eMail: xiang.liu@ctgu.edu.cn

^gState Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, Gansu, P. R. of China eMail: chbh@lzu.edu.cn
Yu Huang

^aCollege of Materials and Chemical Engineering, Key Laboratory of Inorganic Nonmetallic Crystalline and Energy Conversion Materials, China Three Gorges University, Yichang, Hubei 443002, P. R. of China eMail: xiang.liu@ctgu.edu.cn

^gState Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, Gansu, P. R. of China eMail: chbh@lzu.edu.cn
Xu Meng

^bState Key Laboratory for Oxo Synthesis and Selective Oxidation, Suzhou Research Institute of LICP, Lanzhou Institute of Chemical Physics (LICP), Chinese Academy of Sciences, Lanzhou 730000, P. R. of China
Jihui Li

^cCollege of Materials and Chemical Engineering, Hainan University, Haikou 570228, P. R. of China
Dong Wang

^dCenter for AIE Research, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, P. R. of China
Yongxin Chen

^eKey Laboratory of Petroleum Resources, Gansu Province and Key Laboratory of Petroleum Resources Research, Institute of Geology and Geophysics, Chinese Academy of Sciences, Lanzhou 730000, P. R. of China
Dong Tang

^fNingxia Academy of Agriculture and Forestry Sciences, Yinchuan 750002, P. R. of China
Baohua Chen *

^gState Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, Gansu, P. R. of China eMail: chbh@lzu.edu.cn

Abstract

Alle Artikel dieser Rubrik

Dedicated to Professor Dong-Sheng Li on the occasion of his 50th birthday.

Abstract

The synthesis and structure of nitrogen-containing heterocycles are fascinating because these compounds have a great richness of structural, physicochemical, and biological properties. Therefore, the development of improved ways for the synthesis of polyfunctional nitrogen-containing heterocycles continues to be a challenging goal. This account describes developments in the discovery of C–H/N–H bond functionalization and oxidative cyclization procedures for the synthesis of nitrogen-containing heterocycles (aziridines, indoles, indolizines, triazoles, imidazoles, oxazoles, thiazoles, quinoxalines, triazines, and pyridines) in our laboratories during the last 15 years.

1 Introduction

2 Synthesis of Aziridines

3 Synthesis of Indoles and Indolizines

4 Synthesis of Triazoles

5 Synthesis of Imidazoles

6 Synthesis of Oxazoles and Thiazoles

7 Synthesis of Quinoxalines, Triazines, and Pyridines

8 Conclusion and Outlook

Key words

oxidative cyclization - C–H bond activation - nitrogen heterocycles - N–H bond activation

Volltext

Referenzen

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