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Thromb Haemost 1999; 81(04): 582-584
DOI: 10.1055/s-0037-1614528
DOI: 10.1055/s-0037-1614528
Rapid Communication
High Prevalence of Factor V Leiden in Healthy Jordanian Arabs
Authors
Further Information
Publication History
Received
07 August 1998
Accepted after resubmission
24 November 1998
Publication Date:
09 December 2017 (online)
Summary
The prevalence of APC resistance in healthy Jordanian Arabs was studied. Between October 1996 through September 1997 a total of 400 healthy subjects were studied. There were 212 males and 188 females. APC resistance was studied by functional and DNA methods. There were a total of 52 subjects (13%) who were APC resistant by the functional test. There were 49 subjects (12.25%) who had FV Q506 by DNA test. Of these there were 42 heterozygous and 7 homozygous (allele frequency 0.07). None of the subjects had clinical thrombosis. It is concluded that the prevalence of APC resistance due to FV Q506 is high in Jordanian Arabs.
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