Endoscopy 2018; 50(04): S55
DOI: 10.1055/s-0038-1637190
ESGE Days 2018 oral presentations
20.04.2018 – Best abstract awards
Georg Thieme Verlag KG Stuttgart · New York

ENDOCUFF® ASSISTED COLONOSCOPY VERSUS STANDARD COLONOSCOPY IN THE SURVEILLANCE OF THE SERRATED POLYPOSIS SYNDROME. A RANDOMIZED, CONTROLLED AND MULTICENTER TRIAL

, EndoCAR group
L Rivero-Sánchez
1   Hospital Clinic, University of Barcelona, Department of Gastroenterology and Endoscopy, CIBERehd, IDIBAPS, Barcelona, Spain
,
J López Vicente
2   Hospital Universitario de Móstoles, Aparato Digestivo, Móstoles, Spain
,
L Hernandez Villalba
3   Hospital Santos Reyes, Aparato Digestivo, Aranda de Duero, Spain
,
I Puig
4   Xarxa Assistencial Universitaria de Manresa, Aparato Digestivo, Manresa, Spain
,
C Arnau
5   Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
,
L Moreno
6   Fundació Clínic per a la Recerca Biomèdica, Barcelona, Spain
,
M Díaz
5   Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
,
C Rodriguez de Miguel
7   Hospital Clinic, Department of Gastroenterology and Digestive Endoscopy, Barcelona, Spain
,
T Ocaña
7   Hospital Clinic, Department of Gastroenterology and Digestive Endoscopy, Barcelona, Spain
,
L Moreira
1   Hospital Clinic, University of Barcelona, Department of Gastroenterology and Endoscopy, CIBERehd, IDIBAPS, Barcelona, Spain
,
M Cuatrecasas
8   Hospital Clinic, Pathology Department, Barcelona, Spain
,
S Carballal
1   Hospital Clinic, University of Barcelona, Department of Gastroenterology and Endoscopy, CIBERehd, IDIBAPS, Barcelona, Spain
,
A Sánchez
5   Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
,
J Llach
7   Hospital Clinic, Department of Gastroenterology and Digestive Endoscopy, Barcelona, Spain
,
F Balaguer
7   Hospital Clinic, Department of Gastroenterology and Digestive Endoscopy, Barcelona, Spain
,
M Pellisé
1   Hospital Clinic, University of Barcelona, Department of Gastroenterology and Endoscopy, CIBERehd, IDIBAPS, Barcelona, Spain
› Author Affiliations
Further Information

Publication History

Publication Date:
27 March 2018 (online)

Also available at
 

Aims:

Patients with serrated polyposis syndrome (SPS) have an increased risk of colorectal cancer (CRC). This risk decreases during annual endoscopic surveillance. Endocuff® (Arc-Medical-Design, Leeds, UK) is a cap with plastic projections that flatten the colonic folds during removal, improving the visualization of the mucosal surface and detection of lesions. We aimed to evaluate if the Endocuff Assisted Colonoscopy (ECC) improves the detection of the serrated lesions (SL) in the surveillance of patients with SPS in relation to the Standard Colonoscopy (SC).

Methods:

We conducted a study in four Spanish centers with six expert colonoscopists. Patients with SPS (WHO criteria 1 and/or 3) in the surveillance phase (previous resection of all the SL ≥4 mm) were consecutively included and randomized 1:1 to perform ECC or SC with high-definition endoscopes. Quality parameters of the colonoscopy and characteristics of all identified lesions were recorded. Inadequate preparation and incomplete colonoscopy were exclusion criteria

Results:

Out of 128 randomized patients (September 2015 – July 2017) 5 were subsequently excluded due to inadequate bowel preparation. Out of the 123 patients included (59% men, age 61 ± 7 years), 63 were assigned to ECC and 60 to SC. The baseline characteristics (history of CRC, subtotal colectomy, SPS subtype, cumulative number of colonoscopies and lesions) as well as the procedure and withdrawal times were similar between both groups. ECC detected more flat lesions than SC in the right colon (97 vs. 47 p = 0.001) and left lesion (205 vs. 200 p = 0.035), plus flat adenomas in any location (38 vs. 14 p = 0.006) and flat SL in the right colon (56 vs. 26 p = 0.009). There was no difference in the total number of SL between ECC and SC

Conclusions:

ECC may be useful to improve the effectiveness of surveillance colonoscopy in patients with SPS.