Endoscopy 2018; 50(04): S112
DOI: 10.1055/s-0038-1637360
ESGE Days 2018 ePoster Podium presentations
20.04.2018 – Motility disorders
Georg Thieme Verlag KG Stuttgart · New York

A NONINVASIVE ENDOSCOPIC METHOD FOR EVALUATING GASTRIC SLOW WAVE PATTERNS

SH Kim
1   Korea University College of Medicine, Seoul, Korea, Republic of
,
G Min
1   Korea University College of Medicine, Seoul, Korea, Republic of
,
SJ Choi
1   Korea University College of Medicine, Seoul, Korea, Republic of
,
W Kim
1   Korea University College of Medicine, Seoul, Korea, Republic of
,
JM Lee
1   Korea University College of Medicine, Seoul, Korea, Republic of
,
JM Lee
1   Korea University College of Medicine, Seoul, Korea, Republic of
,
HS Choi
1   Korea University College of Medicine, Seoul, Korea, Republic of
,
ES Kim
1   Korea University College of Medicine, Seoul, Korea, Republic of
,
B Keum
1   Korea University College of Medicine, Seoul, Korea, Republic of
,
YT Jeen
1   Korea University College of Medicine, Seoul, Korea, Republic of
,
HS Lee
1   Korea University College of Medicine, Seoul, Korea, Republic of
,
HJ Chun
1   Korea University College of Medicine, Seoul, Korea, Republic of
,
CD Kim
1   Korea University College of Medicine, Seoul, Korea, Republic of
› Author Affiliations
Further Information

Publication History

Publication Date:
27 March 2018 (online)

Also available at
 

Aims:

Gastric slow waves regulate peristalsis, and gastric dysrhythmias have been implicated in functional motility disorders. Until now, to accurately define slow wave patterns, it is necessary to measure high-resolution serosal recordings during open surgery, which is invasive and limit their application. We therefore devised a novel and noninvasive gastric slow wave mapping method which can be performed during endoscopic procedures. We aimed to assess feasibility of endoscopic mucosal mapping method comparing to serosal mapping method and quantify correspondence between the two techniques.

Methods:

Acquisition of gastric electrical signals was performed on healthy fasted weaner pigs under general anesthesia. Recordings were performed using endoscopic probe in followed lesions:

  1. gastric mucosal surface

  2. gastric serosal surface.

All of these site were held constant on 5 cm from lesser curvature. A multi-channel recorder (Acknowledge 4.4, MP150; Biopac Systems, Santa Barbara, CA) was used to record gastric myoelectrical activity throughout the study. We compared gastric electrical signals between gastric mucosal and serosal surface according to various lesions.

Results:

Bipolar recording electrodes were directed to fundus, body, and antrum area. Gastric slow wave activity was successfully recorded simultaneously via both the novel endoscopic method and the serosal measurement in all five porcine trials. Dominant frequencies at all sites were 2.96 ± 0.07 cycles min-1 (cpm). Powers of the dominant frequency were similar between the two methods. Recordings from the mucosa and serosa array in pigs were identical in frequency, and activation patterns and velocities were consistent.

Conclusions:

In conclusion, the novel endoscopic method achieves high quality gastric mucosal slow wave recordings. The new techniques and findings described here offer new opportunities for endoscopic gastric electrical signal aquisition method in patients with gastric motility disorder.