Endoscopy 2018; 50(04): S144
DOI: 10.1055/s-0038-1637463
ESGE Days 2018 ePosters
Georg Thieme Verlag KG Stuttgart · New York

ERYTHROCYTE DISTRIBUTION WIDTH (RDW) AND HELICOBACTER PYLORI (H. PYLORI) INFECTION: IS THERE AN ASSOCIATION?

B Çavuş
1   Bingöl State Hospital, Gastroenterology, Bingöl, Turkey
,
T Çavuş
2   Kırklareli State Hospital, Internal Medicine, Kırklareli, Turkey
,
B Akyüz Erdoğan
3   Bingöl State Hospital, Pathology, Bingöl, Turkey
,
E Kumcu
3   Bingöl State Hospital, Pathology, Bingöl, Turkey
› Author Affiliations
Further Information

Publication History

Publication Date:
27 March 2018 (online)

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Aims:

H. Pylori is thought to be associated with inflammation and anemia. Although RDW's relationship with many diseases and inflammatory processes has been investigated, there is no study in the literature to show its relationship with H. Pylori. We aimed to investigate the relationship between RDW and H. Pylori in this study.

Methods:

We included 229 patients who underwent gastroscopic evaluation for various reasons and biopsied from the antrum between February-July 2017. Patients were divided into two groups based on H. pylori detected and undetected by pathological evaluation. Hemogram and biochemical parameters were recorded from the outpatient clinic files of the patients.

Results:

H. pylori positivity was determined as 39.3% in all patients, and this rate was 36.8% in males and 42% in females. In patients with H. pylori (+), the mean of RDW-CV was 13.84, and the mean RDW-CV was 13.83 in the negative-detected group. The average level of CRP was identified as 0.51 in the group of H. Pylori (+), and 0.34 in the negative patient group. There was no statistically significant difference between the two groups (p = 0.531). When the correlation between the RDW-CV and CRP, iron parameters, vitamin B12 and folate levels were evaluated, there was a negative correlation with iron, transferrin saturation and ferritin (p =< 0.01, p =< 0.01, p = 0.01 respectively). The mean of RDW-CV in the patients with intestinal metaplasia (IM) in the biopsy results was 14.39, the mean of RDW-CV was 13.73 in the non-detected patient group. The mean of RDW-CV of patients with atrophy in the pathological evaluation was 14.15 and the mean of RDW-CV was 13.73 in the group of non-detected atrophy.

Conclusions:

We evaluated the association of RDW-CV with H. pylori and a statistical difference between H. pylori positive and negative group was not detected (p = 0.46). In the group of patients with IM, it is detected that the RDW-CV is higher than the non-detectable IM group and it is statistically significant (p = 0.039).