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DOI: 10.1055/s-0038-1637563
ACUTE COLONIC OBSTRUCTION CAUSED BY LEFT COLO-RECTAL CANCER. FACTORS RELATED TO MORTALITY AND RECURRENCE
Publication History
Publication Date:
27 March 2018 (online)
Aims:
To evaluate factors involved in mortality and recurrence in patients who presented an acute colonic obstruction secondary to left colon cancer.
Methods:
We performed an observational and retrospective study of patients attended in a single center for acute left colonic obstruction caused by cancer between 2007 and 2014. There were only included patients with curative intention, without metastasis at the time of diagnosis and treated with surgery with R0 resection.
Results:
There were included 106 patients, who were followed for 4,1 ± 2,6 years. It was placed a colonic stent as a bridge in 76 (71,7%), and the rest were operated in an emergency setting. Technical success in stent placement was achieved in 69 patients (90,8%), and clinical success in 63 (82,9%). Perforation due to stent took place in 3 patients (4,9%). Mortality was related in the univariate analysis to age, (HR 1,08, p = 0,000), Charlson score (HR 1,24, p = 0,014), chemotherapy (HR 0,26, p = 0,000) and recurrence (HR 3,23, p = 0,001). In the multivariate analysis only age (HR 1,08, p = 0,000) and recurrence (HR 2,89, p = 0,003) were related to higher mortality. Nor tumoral stage neither stent placement were related to mortality.
Recurrence was not related to any basal feature, stent placement, histology or stage in the univariate or multivariate analysis.
Conclusions:
Factors related to mortality in acute left side colonic obstruction treated with curative intention are age and tumoral recurrence. Placement of a colonic stent does not increase mortality or tumoral recurrence.