Clin Colon Rectal Surg 2018; 31(05): 295-300
DOI: 10.1055/s-0038-1642053
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Gastrointestinal Stromal Tumors of the Distal Gastrointestinal Tract

Katherine A. Kelley
1  Division of Gastrointestinal and General Surgery, Department of Surgery, Oregon Health & Science University, Portland, Oregon
,
Raphael Byrne
1  Division of Gastrointestinal and General Surgery, Department of Surgery, Oregon Health & Science University, Portland, Oregon
,
Kim C. Lu
1  Division of Gastrointestinal and General Surgery, Department of Surgery, Oregon Health & Science University, Portland, Oregon
› Author Affiliations
Further Information

Publication History

Publication Date:
04 September 2018 (online)

Abstract

Gastrointestinal stromal tumors (GISTs) are rare in occurrence, but comprise the most common mesenchymal tumors of the gastrointestinal tract and affect between 15 and 20 individuals per million per year. Due to recent advancements in molecular classification of these tumors, medical therapy has provided improved outcomes to a historically surgically managed disease. This review article briefly discusses the molecular characteristics, medical and surgical therapies, and future of GIST management.