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Journal of Pediatric Neurology 2019; 17(03): 128-130
DOI: 10.1055/s-0038-1656532
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Paroxysmal Autonomic Instability with Dystonia Syndrome in Association with Wolf–Hirschhorn Syndrome

Rachel Manalo
1   Division of Pediatric Cardiology, Department of Pediatrics, Holtz Children's Hospital, Jackson Memorial Hospital, Miami, Florida, United States
,
Marioxy Contreras
1   Division of Pediatric Cardiology, Department of Pediatrics, Holtz Children's Hospital, Jackson Memorial Hospital, Miami, Florida, United States
,
Sudheer R. Gorla
1   Division of Pediatric Cardiology, Department of Pediatrics, Holtz Children's Hospital, Jackson Memorial Hospital, Miami, Florida, United States
,
Mary C. Sokoloski
2   Division of Pediatric Cardiology, Department of Pediatrics, University of Miami/Miller School of Medicine, Miami, Florida, United States
,
Richard E. Kardon
2   Division of Pediatric Cardiology, Department of Pediatrics, University of Miami/Miller School of Medicine, Miami, Florida, United States
› Author Affiliations Funding This research received no grant from any funding agency, commercial, or not-for-profit sectors.
Further Information

Publication History

02 March 2018

24 April 2018

Publication Date:
25 May 2018 (online)

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Abstract

Paroxysmal autonomic instability with dystonia (PAID) syndrome, a distinct entity of autonomic dysfunction, is typically seen following acute brain injury. There are no reported cases of this entity in association with Wolf–Hirschhorn syndrome (WHS). Here, we report a case of WHS whose predominant neurological manifestations were consistent with PAID syndrome.

Keywords

Wolf–Hirschhorn syndrome - PAID syndrome - beta blockers

Authors' Contributions

Dr. Manalo and Dr. Contreras drafted the initial manuscript.


Dr. Gorla reviewed and revised the manuscript.


Dr. Kardon and Dr. Sokoloski critically reviewed and revised the manuscript.


All authors approved the final manuscript as submitted and agreed to be accountable for all aspects of the work.


Ethical Standards

Not required.


 

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