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CC BY-NC-ND 4.0 · Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery 2018; 37(03): 223-226
DOI: 10.1055/s-0038-1668173
Case Report | Relato de Caso
Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil

Olfactory Groove Schwannoma—A Case Report and Literature Review

Schwannoma de Goteira Olfatória—Relato de Caso e Revisão de Literatura
Marcelo Pedrotti De Cesaro
1   Faculty of Medicine, Universidade de Passo Fundo, Passo Fundo, RS, Brazil
,
Moisés Augusto Araújo
2   Department of Neurosurgery, Hospital da Cidade de Passo Fundo, Passo Fundo, RS, Brazil
,
Fernada de Carli
1   Faculty of Medicine, Universidade de Passo Fundo, Passo Fundo, RS, Brazil
,
Gregori Manfroi
1   Faculty of Medicine, Universidade de Passo Fundo, Passo Fundo, RS, Brazil
,
Daniela Schwingel
3   School of Medicine, Instituto Meridional, Passo Fundo, RS, Brazil
4   Instituto de Patologia de Passo Fundo, Passo Fundo, RS, Brazil
,
Paulo Moacir Mesquita Filho
2   Department of Neurosurgery, Hospital da Cidade de Passo Fundo, Passo Fundo, RS, Brazil
3   School of Medicine, Instituto Meridional, Passo Fundo, RS, Brazil
5   Neurology and Neurosurgery Service, Passo Fundo, RS, Brazil
› Author Affiliations
Further Information

Publication History

01 February 2018

08 June 2018

Publication Date:
20 August 2018 (online)

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Abstract

Olfactory groove schwannomas (OGSs) are rare benign tumors of the anterior skull base region. Considering the lack of Schwann cells in the optic and olfactory nerves, their origin remains enigmatic. Despite the precursor cell, total resection of the lesion is curative, as long as the histopathological features of the tumor are compatible with schwannoma. We report the case of a 32-year-old woman, addicted to crack, who was brought to the hospital presenting with cognitive dysfunction after being physically assaulted, whose neuroimaging revealed a large extra-axial mass in the subfrontal sagittal region. The presentation, immunohistochemical markers and histogenesis are discussed in the present study, along with a literature review.

Resumo

O schwannoma da goteira olfatória (SGO) é um tipo de tumor raro da região anterior da base do crânio. Devido à inexistência de células de Schwann nos nervos óptico e olfatório, a origem desses tumores permanece enigmática. Independentemente da célula precursora, a ressecção total do tumor demonstrou ser curativa, desde que o tumor apresente características histopatológicas condizentes com schwannoma. Relatamos aqui o caso de uma mulher de 32 anos, dependente de crack, que foi trazida ao hospital apresentando disfunção cognitiva após sofrer agressão física. A neuroimagem revelou uma grande massa extra-axial se estendendo desde a goteira olfatória até a região entre os hemisférios frontais. A paciente foi submetida a tratamento cirúrgico, e o tumor foi removido completamente. A apresentação clínica, marcadores imunohistoquímicos e a histopatogênese são discutidos no presente estudo, juntamente com uma revisão da literatura.

Keywords

olfactory groove schwannoma - olfactory ensheathing cell tumor - anterior skull base - neuroimaging - immunohistochemical - anosmia

Palavras-chave

schwannoma da goteira olfatória - tumor de células envoltórias olfativas - base do crânio anterior - neuroimagem - imunohistoquímica - anosmia
 

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