Download PDF
Zeitschrift für Komplementärmedizin 2018; 10(05): 56-61
DOI: 10.1055/s-0038-1675318
Wissen
Blutspende und Hypertonie
© Karl F. Haug Verlag in MVS Medizinverlage Stuttgart GmbH & Co. KG

Blutspende – Behandlungsoption bei Hypertonie?

Julian Kamhieh-Milz
,
Yvonne Tauchmann
,
Axel Pruß
,
Yvonne Dörffel
,
Andreas Michalsen
Subject Editor:
Further Information

Publication History

Publication Date:
04 October 2018 (online)

    Permissions and Reprints

Summary

Der Aderlass zählt zu den wichtigsten traditionellen Behandlungsverfahren der traditionellen Medizin in den unterschiedlichsten Kulturen. Das zwischenzeitlich durch missbräuchliche Anwendung in Ungnade gefallene Verfahren hat sich heute z.B. zur Behandlung von Patienten mit Hämochromatose und Polycythaemiaverawieder etabliert.

In den letzten Jahren konnten positive Ergebnisse bei therapierefraktärem Hypertonus gezeigt werden. So konnte im Rahmen von Studien bei Patienten nach Nierentransplantation und bei Patienten mit metabolischem Syndrom der Blutdruck durch Aderlass erfolgreich gesenkt werden. Weitere Forschungsarbeit zu den vielversprechenden Ergebnissen ist allerdings notwendig, um die Ergebnisse zu untermauern.

Perspektiven ergeben sich zudem in Anbetracht der zunehmenden Blutknappheit. Allerdings steht die Klärung ethischer Fragestellungen noch aus.

Keywords

Hypertonie - Aderlass - Blutspende
 

  • Literatur

  • 1 WorldHealthOrganization, Cardiovascular diseases (CVDs) http://www. who.int/mediacentre/factsheets/fs317/en/ Accessed February 7, 2012.
  • 2 Atsma F, Veldhuizen I, de Kort W. et al Hemoglobin level is positively associated with blood pressure in a large cohort of healthy individuals. Hypertension 2012; 60: 936-941
    CrossrefPubMedGoogle Scholar
  • 3 Lawes CM, Vander Hoorn S, Rodgers A. International Society of Hypertension. Global burden of blood-pressure-related disease, 2001. Lancet 2008; 371: 1513-1518
    CrossrefPubMedGoogle Scholar
  • 4 Chobanian AV. Mixed messages on blood pressure goals. Hypertension 2011; 57: 1039-1040
    CrossrefPubMedGoogle Scholar
  • 5 Gaziano TA, Bitton A, Anand S, Weinstein MC. International Society of Hypertension. The global cost of nonoptimal blood pressure. J Hypertens 2009; 27: 1472-1477
    CrossrefPubMedGoogle Scholar
  • 6 Whelton PK, Carey RM, Aronow WS. et al 2017 ACC / AHA / AAPA / ABC / ACP M / AGS / APhA / ASH / ASPC / NMA / PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology / American Heart Association Task Force on Clinical Practice Guidelines. Hypertension 2018; 71 (06) 1269-1324
    CrossrefPubMedGoogle Scholar
  • 7 Parapia LA. History of bloodletting by phlebotomy. Br J Haematol 2008; 143: 490-495
    CrossrefPubMedGoogle Scholar
  • 8 Sullivan JL. Blood donation may be good for the donor. Iron, heart disease, and donor recruitment. Vox Sang 1991; 61: 161-164
    PubMedGoogle Scholar
  • 9 Salonen JT, Tuomainen TP, Salonen R. et al Donation of blood is associated with reduced risk of myocardial infarction. The Kuopio Ischaemic Heart Disease Risk Factor Study. Am J Epidemiol 1998; 148: 445-451
    CrossrefPubMedGoogle Scholar
  • 10 Nilsson Sojka B, Sojka P. The blood-donation experience: perceived physical, psychological and social impact of blood donation on the donor. Vox Sang 2003; 84: 120-128
    CrossrefPubMedGoogle Scholar
  • 11 Greinacher A, Fendrich K, Hoffmann W. Demographic changes: the impact for safe blood supply. Transfus Med Hemother 2010; 37: 141-148
    CrossrefPubMedGoogle Scholar
  • 12 Barenbrock M, Spieker C, Rahn KH. et al Therapeutic efficiency of phlebotomy in posttransplant hypertension associated with erythrocytosis. Clin Nephrol 1993; 40: 241-243
    PubMedGoogle Scholar
  • 13 Houschyar KS, Ludtke R, Dobos GJ. et al Effects of phlebotomy-induced reduction of body iron stores on metabolic syndrome: results from a randomized clinical trial. BMC Med 2012; 10: 54
    CrossrefPubMedGoogle Scholar
  • 14 Kamhieh-Milz S, Kamhieh-Milz J, Tauchmann Y. et al. Regular blood donation may help in the management of hypertension: an observational study on 292 blood donors. Transfusion 2016; 56: 637-644
    CrossrefPubMedGoogle Scholar
  • 15 Lundberg JO, Weitzberg E, Gladwin MT. The nitrate-nitrite-nitric oxide pathway in physiology and therapeutics. Nat Rev Drug Discov 2008; 7: 156-167
    CrossrefPubMedGoogle Scholar
  • 16 Cabrales P, Sun G, Zhou Y. et al Effects of the molecular mass of tense-state polymerized bovine hemoglobin on blood pressure and vasoconstriction. J Appl Physiol (1985) 2009; 107: 1548-1558
    CrossrefPubMedGoogle Scholar
  • 17 Cabrales P, Han G, Nacharaju P. et al Reversal of hemoglobin-induced vasoconstriction with sustained release of nitric oxide. Am J Physiol Heart Circ Physiol 2011; 300: H49-56
    CrossrefPubMedGoogle Scholar
  • 18 Meyers DG, Jensen KC, Menitove JE. A historical cohort study of the effect of lowering body iron through blood donation on incident cardiac events. Transfusion 2002; 42: 1135-1139
    CrossrefPubMedGoogle Scholar
  • 19 Zheng H, Cable R, Spencer B. et al Iron stores and vascular function in voluntary blood donors. Arterioscler Thromb Vasc Biol 2005; 25: 1577-1583
    CrossrefPubMedGoogle Scholar
  • 20 Tuomainen TP, Salonen R, Nyyssonen K. et al Cohort study of relation between donating blood and risk of myocardial infarction in 2682 men in eastern Finland. BMJ 1997; 314: 793-794
    CrossrefPubMedGoogle Scholar
  • 21 Holsworth Jr. RE, Cho YI, Weidman JJ. et al Cardiovascular benefits of phlebotomy: relationship to changes in hemorheological variables. Perfusion 2014; 29: 102-116
    CrossrefPubMedGoogle Scholar
  • 22 Ritter S, Willand L, Reinhard B. et al. [Demography and donation frequencies of blood and plasma donor populations in Germany]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2008; 51: 915-925
    CrossrefPubMedGoogle Scholar