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CC BY-NC-ND 4.0 · AJP Rep 2018; 08(04): e277-e279
DOI: 10.1055/s-0038-1675336
Case Report
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Early-Onset Neonatal Sepsis with Extended Spectrum Beta-Lactamase Producing Escherichia Coli in Infants Born to South and South East Asian Immigrants: A Case Series

Kalsang Dolma
1   Division of Neonatology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama
,
Thanh L. Summerlin
1   Division of Neonatology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama
,
Hansa Wongprasert
1   Division of Neonatology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama
,
Charitharth Vivek Lal
1   Division of Neonatology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama
,
Joseph B. Philips III
1   Division of Neonatology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama
,
Lindy Winter
1   Division of Neonatology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama
› Author Affiliations Funding Source No funding was secured for this study.
Further Information

Publication History

15 June 2018

03 August 2018

Publication Date:
29 October 2018 (online)

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Abstract

Extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae represent a major worldwide threat. We present three cases of early onset ESBL Escherichia coli sepsis in infants born to families from South and Southeast Asia to inform the practitioner community about this emerging threat. Infants with suspected sepsis, whose mother is from Asia or Southeast Asia, should be suspected of having an infection with an ESBL-producing organism, and practitioners should strongly consider adding a carbapenem to their usual initial antibiotic regimen.

Keywords

neonatal sepsis - early onset sepsis - extended-spectrum β-lactamases - Escherichia coli

Financial Disclosure

The authors have no financial relationships relevant to this article to disclose.


 

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