Download PDF
CC BY 4.0 · Rev Bras Ginecol Obstet 2019; 41(02): 124-128
DOI: 10.1055/s-0038-1676110
Case Report
Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil

Imaging Description of Extragenital Müllerian Adenosarcoma: A Case Report

Descrição da imagem do adenosarcoma mülleriano extragenital: relato de caso
Annalisa Mone 
1   Department of Radiology, University of Verona, Verona, Italy
,
Piergiorgio Iannone
2   Section of Obstetrics and Gynecology, Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy
› Author Affiliations
Further Information

Publication History

28 August 2018

09 October 2018

Publication Date:
12 December 2018 (online)

   Permissions and Reprints

Abstract

Müllerian adenosarcoma is a very rare gynecological disease, comprising 5% of uterine sarcomas. Extragenital localizations are even rarer. We report a very interesting case of a 27-year-old woman complaining of pelvic pain, with a subsequent diagnosis of extragenital Müllerian adenosarcoma. This is the first case reported in the literature with a complete and wide imaging description. Even if rare, Müllerian adenosarcoma should be hypothesized in case of young female patients presenting with suspicious pelvic mass.

Resumo

O adenosarcoma Mülleriano é uma doença ginecológica muito rara, compreendendo 5% dos sarcomas uterinos. Localizações extragenitais são ainda mais raras. Relatamos um caso muito interessante de uma mulher de 27 anos queixando-se de dor pélvica com diagnóstico subsequente de adenosarcoma Mülleriano extragenital. Este é o primeiro caso relatado na literatura com uma descrição completa e ampla de imagem. Mesmo que raro, o adenosarcoma Mülleriano deve ser hipotetizado no caso de pacientes jovens do sexo feminino com massa pélvica suspeita.

Keywords

extragenital müllerian adenosarcoma - computed tomography - pelvic mass - uterine sarcoma

Palavras-chave

adenosarcoma mülleriano extragenital - tomografia computadorizada - massa pélvica - sarcoma uterino
 

  • References

  • 1 Guidozzi F, Smith T, Koller AB, Reinecke L. Management of uterine Müllerian adenosarcoma with extrauterine metastatic deposits. Gynecol Oncol 2000; 77 (03) 464-466
    CrossrefPubMedGoogle Scholar
  • 2 Abeler VM, Røyne O, Thoresen S, Danielsen HE, Nesland JM, Kristensen GB. Uterine sarcomas in Norway. A histopathological and prognostic survey of a total population from 1970 to 2000 including 419 patients. Histopathology 2009; 54 (03) 355-364 Doi: 10.1111/j.1365-2559.2009.03231.x
    CrossrefPubMedGoogle Scholar
  • 3 McCluggage WG. Mullerian adenosarcoma of the female genital tract. Adv Anat Pathol 2010; 17 (02) 122-129 Doi: 10.1097/PAP.0b013e3181cfe732
    CrossrefPubMedGoogle Scholar
  • 4 D'Angelo E, Prat J. Uterine sarcomas: a review. Gynecol Oncol 2010; 116 (01) 131-139 Doi: 10.1016/j.ygyno.2009.09.023
    CrossrefPubMedGoogle Scholar
  • 5 Patrelli TS, Gizzo S, Di Gangi S, Guidi G, Rondinelli M, Nardelli GB. Cervical Mullerian adenosarcoma with heterologous sarcomatous overgrowth: a fourth case and review of literature. BMC Cancer 2011; 11: 236 Doi: 10.1186/1471-2407-11-236
    CrossrefPubMedGoogle Scholar
  • 6 Friedlander ML, Covens A, Glasspool RM. , et al. Gynecologic Cancer InterGroup (GCIG) consensus review for mullerian adenosarcoma of the female genital tract. Int J Gynecol Cancer 2014; 24 (09) (Suppl. 03) S78-S82 Doi: 10.1097/IGC.0000000000000239
    CrossrefPubMedGoogle Scholar
  • 7 Akhavan A, Akhavan Tafti M, Aghili F, Navabii H. Uterine adenosarcoma in a patient with history of breast cancer and long-term tamoxifen consumption. BMJ Case Rep 2012; 2012: bcr2012006590 Doi: 10.1136/bcr-2012-006590
    Google Scholar
  • 8 Press MF, Scully RE. Endometrial “sarcomas” complicating ovarian thecoma, polycystic ovarian disease and estrogen therapy. Gynecol Oncol 1985; 21 (02) 135-154 Doi: 10.1016/0090-8258(85)90246-X
    CrossrefPubMedGoogle Scholar
  • 9 McCluggage WG. A practical approach to the diagnosis of mixed epithelial and mesenchymal tumours of the uterus. Mod Pathol 2016; 29 (Suppl. 01) S78-S91 Doi: 10.1038/modpathol.2015.137
    CrossrefPubMedGoogle Scholar
  • 10 Clement PB, Scully RE. Mullerian adenosarcoma of the uterus: a clinicopathologic analysis of 100 cases with a review of the literature. Hum Pathol 1990; 21 (04) 363-381
    CrossrefPubMedGoogle Scholar
  • 11 Clement PB, Scully RE. Uterine tumors with mixed epithelial and mesenchymal elements. Semin Diagn Pathol 1988; 5 (02) 199-222
    PubMedGoogle Scholar
  • 12 Huang GS, Arend RC, Sakaris A, Hebert TM, Goldberg GL. Extragenital adenosarcoma: a case report, review of the literature, and management discussion. Gynecol Oncol 2009; 115 (03) 472-475 Doi: 10.1016/j.ygyno.2009.07.033
    CrossrefPubMedGoogle Scholar
  • 13 Yang C, Oh HK, Kim D. Müllerian adenosarcoma arising from rectal endometriosis. Ann Coloproctol 2014; 30 (05) 232-236 Doi: 10.3393/ac.2014.30.5.232
    CrossrefPubMedGoogle Scholar
  • 14 Kar R, Verma SK, Papa D, Sylvia MT. Extrauterine adenosarcoma arising in omental endometriosis: rare site of occurrence of a rare tumor. Indian J Pathol Microbiol 2014; 57 (04) 640-641 Doi: 10.4103/0377-4929.142720
    CrossrefPubMedGoogle Scholar
  • 15 Chang HY, Changchien CC, Chen HH, Lin H, Huang CC. Extrauterine müllerian adenosarcoma associated with endometriosis and rectal villotubular adenoma: report of a case and review of the literature. Int J Gynecol Cancer 2005; 15 (02) 361-365 Doi: 10.1111/j.1525-1438.2005.15230.x
    CrossrefPubMedGoogle Scholar
  • 16 Raffaelli R, Piazzola E, Zanconato G, Fedele L. A rare case of extrauterine adenosarcoma arising in endometriosis of the rectovaginal septum. Fertil Steril 2004; 81 (04) 1142-1144 Doi: 10.1016/j.fertnstert.2003.09.053
    CrossrefPubMedGoogle Scholar
  • 17 Liu L, Davidson S, Singh M. Müllerian adenosarcoma of vagina arising in persistent endometriosis: report of a case and review of the literature. Gynecol Oncol 2003; 90 (02) 486-490 Doi: 10.1016/S0090-8258(03)00266-X
    CrossrefPubMedGoogle Scholar
  • 18 Murugasu A, Miller J, Proietto A, Millar E. Extragenital mullerian adenosarcoma with sarcomatous overgrowth arising in an endometriotic cyst in the pouch of Douglas. Int J Gynecol Cancer 2003; 13 (03) 371-375
    CrossrefPubMedGoogle Scholar
  • 19 Judson PL, Temple AM, Fowler Jr WC, Novotny DB, Funkhouser Jr WK. Vaginal adenosarcoma arising from endometriosis. Gynecol Oncol 2000; 76 (01) 123-125 Doi: 10.1006/gyno.1999.5617
    CrossrefPubMedGoogle Scholar
  • 20 Fukunaga M, Ishihara A, Ushigome S. Extrauterine low-grade endometrial stromal sarcoma: report of three cases. Pathol Int 1998; 48 (04) 297-302 Doi: 10.1111/j.1440-1827.1998.tb03909.x
    CrossrefPubMedGoogle Scholar
  • 21 Kumar S, Raza M, Tariq MU. Low grade Mullerian adenosarcoma of pouch of Douglas recurring as bilateral ovarian high grade Mullerian adenosarcoma with rhabdomyosarcomatous overgrowth after 11 years. J Pak Med Assoc 2018; 68 (08) 1263-1266
    PubMedGoogle Scholar
  • 22 Shetty M, Lal N, Vu NH. Müllerian adenosarcoma of the ovary: case report and review of the literature. Ultrasound Q 2007; 23 (03) 189-191 Doi: 10.1097/RUQ.0b013e31814b94f7
    CrossrefPubMedGoogle Scholar
  • 23 Kanngurn S, Somran J, Art-Ong C, Lamlertthon W, Porncharoenpong S. Primary peritoneal adenosarcoma with stromal overgrowth and fetal type cartilage: a case report and literature review. J Med Assoc Thai 2005; 88 (06) 849-854
    PubMedGoogle Scholar
  • 24 Hirakawa E, Kobayashi S, Miki H. , et al. Ascitic fluid cytology of adenosarcoma of the ovary: a case report. Diagn Cytopathol 2001; 24 (05) 343-346 Doi: 10.1002/dc.1074
    CrossrefPubMedGoogle Scholar
  • 25 Kato N, Zhe J, Endoh Y, Motoyama T. Extrauterine Müllerian adenosarcoma of the peritoneum with an extensive rhabdomyosarcomatous element and a marked myxoid change. Pathol Int 2000; 50 (04) 347-351 Doi: 10.1046/j.1440-1827.2000.01039.x
    CrossrefPubMedGoogle Scholar