J Pediatr Neurol
DOI: 10.1055/s-0039-1688975
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Dengue Infection: Not Just Fever—A Rare Presentation with Literature Review

1  Department of Neurology, Jubilee Mission Medical College and Research Institute, Thrissur, Kerala, India
,
Percival Gilvaz
1  Department of Neurology, Jubilee Mission Medical College and Research Institute, Thrissur, Kerala, India
,
Rati Santhakumar
2  Department of Pediatrics, Jubilee Mission Medical College and Research Institute, Thrissur, Kerala, India
,
Aneesh Mangalasseril Kuriakose
3  Department of Radiology, Jubilee Mission Medical College and Research Institute, Thrissur, Kerala, India
› Author Affiliations
Funding None.
Further Information

Publication History

01 February 2019

14 April 2019

Publication Date:
29 May 2019 (online)

Abstract

Dengue fever is a common viral infection in the tropical areas, especially in India. However, dengue infection presenting as hemorrhagic encephalitis is rare. A 10-year-old girl presented with fever, headache, vomiting, and seizures followed by altered sensorium. Her blood serum was positive for antidengue immunoglobulin M enzyme-linked immunosorbent assay (ELISA) and NS1Ag, and cerebrospinal fluid study showed lymphocytic pleocytosis. Magnetic resonance imaging T2-weighted and fluid-attenuated inversion recovery (FLAIR) images showed hyperintensities involving the bilateral thalami, pons, and midbrain with patchy hemorrhage. Despite all supportive measures, she expired 3 days after admission. Our case highlights that dengue encephalitis may present even in the absence of other classical signs.

Key Messages

1. Dengue encephalitis is a rare manifestation of dengue fever.


2. Dengue encephalitis may present even in the absence of classical clinical features of dengue fever.


Authors' Contributions

N.B.: Data collection, literature review, and preparation of the manuscript. P.C.G.: Conceptualized and supervised the data, critically reviewed the article, and will act as guarantor for the article. R.S.: Supervised the data and critically reviewed the article. A.M.K.: Data acquisition and critically reviewed the article