J Pediatr Neurol
DOI: 10.1055/s-0039-1692451
Review Article
Georg Thieme Verlag KG Stuttgart · New York

Behçet's Disease from Rheumatology and Neurology Perspectives with Special Reference to Children

Yaşar B. Turgut
1  Department of Internal Medicine, Muğla Sıtkı Koçman University School of Medicine, Muğla, Turkey
,
Ayşe F. Tosun
2  Department of Pediatric Neurology, Adnan Menderes University School of Medicine, Aydın, Turkey
,
Beste K. Yüzbaşı
3  Clinic of Pediatric Neurology, Denizli State Hospital, Denizli, Turkey
,
Hasan Tunca
1  Department of Internal Medicine, Muğla Sıtkı Koçman University School of Medicine, Muğla, Turkey
› Author Affiliations
Further Information

Publication History

08 April 2019

08 May 2019

Publication Date:
01 July 2019 (online)

Abstract

Behçet's disease (BD) is an idiopathic chronic relapsing multisystemic vascular inflammatory disease. Although it is generally seen in young adults with male predominance, the onset age of the disease is the pediatric age group in only 4 to 26% of all cases of BD. According to the International Study Group for Behçet's Disease Classification Criteria, a diagnosis of BD requires recurrent oral aphthous ulcerations with two of the following: genital ulcerations, skin lesions, eye lesions, or a positive pathergy test. In this article, we extensively reviewed the current literature with respect to the rheumatological and neurological findings of BD in childhood.