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CC BY 4.0 · Rev Bras Ginecol Obstet 2019; 41(10): 628-632
DOI: 10.1055/s-0039-1698773
Case Report
Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil

Rare Case of Sarcomatoid Squamous Cell Carcinoma Arising in an Ovarian Mature Teratoma

Caso raro de carcinoma espinocelular sarcomatoide que surge em um teratoma ovariano maduro
Isabel Sofia de Sousa Pedrosa 
1   Centro Hospitalar do Baixo Vouga, Aveiro, Portugal
,
Filipa da Cunha Almeida Alpendre
2   Centro Hospitalar Lisboa Central, Lisboa, Portugal
,
Rita Sousa
3   Instituto Português de Oncologia Francisco Gentil, Coimbra, Portugal
,
Sofia Raposo Dinis
3   Instituto Português de Oncologia Francisco Gentil, Coimbra, Portugal
,
Daniela Gomes
3   Instituto Português de Oncologia Francisco Gentil, Coimbra, Portugal
› Author Affiliations
Further Information

Publication History

14 July 2019

16 September 2019

Publication Date:
28 October 2019 (online)

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Abstract

Although mature cystic teratoma (MCT) is benign, malignant transformation (MT) occurs in ∼ 1% to 2% of all cases, and usually consists of squamous cell carcinoma (SCC), which accounts for ∼ 80% of the cases. Spindle-cell (sarcomatoid) carcinoma (SCSC) is an uncommon type of SCC, comprising up to 3% of all cases. The lack of characteristic symptoms and specific imaging findings may lead to preoperative misdiagnosis. Moreover, the clinicopathologic characteristics, the treatment, the prognostic factors and the mechanism of MT have not yet been well understood due to the rarity of such tumors, especially in women of reproductive age. The authors present a case of a 34-year-old patient with 14 weeks of gestation who was diagnosed with an adnexal mass suggestive of ovarian teratoma. A laparoscopy salpingo-oophorectomy was performed after 6 months of delivery, and the histological exam revealed a sarcomatoid SCC in the MCT.

Resumo

Embora o teratoma cístico maduro (MCT) seja benigno, a transformação maligna (MT) ocorre em cerca de 1% a 2% dos casos, e geralmente apresenta-se sob a forma de carcinoma espinocelular (CEC), responsável por cerca de 80% dos casos. O carcinoma (sarcomatoide) de células fusiformes (CSCF) é um tipo incomum de CEC, compreendendo até 3% de todos os casos. A falta de sintomas característicos e achados imagiológicos específicos pode levar a erros diagnósticos pré-operatórios. Além disso, as características clinico-patológicas, o tratamento, os fatores prognósticos e o mecanismo da MT ainda não são bem compreendidos devido à raridade de tais tumores, principalmente em mulheres em idade reprodutiva. Os autores apresentam um caso de uma paciente de 34 anos com 14 semanas de gestação que foi diagnosticada com uma massa anexial sugestiva de teratoma do ovário. A anexectomia laparoscópica foi realizada após 6 meses do parto, e o exame histológico revelou um CEC sarcomatoide tendo como origem um MCT.

Keywords

squamous cell carcinoma - ovarian mature teratoma - pregnant women

Palavras-chave

carcinoma de células escamosas - teratoma maduro ovariano - gestantes
 

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