Endoscopy 2020; 52(S 01): S220
DOI: 10.1055/s-0040-1704687
ESGE Days 2020 ePoster Podium presentations
Saturday, April 25, 2020 11:30 – 12:00 Pancreatic cancer diagnosis ePoster Podium 3
© Georg Thieme Verlag KG Stuttgart · New York

PROGNOSIS AND CLINICAL CHARACTERISTICS OF PANCREATIC CANCER PATIENTS DIAGNOSED WITH ENDOSCOPIC ULTRASOUND BUT INDETERMINATE ON CT: A MULTI-CENTER RETROSPECTIVE COHORT STUDY

Tae Jun Song
1   University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea, Republic of
,
SW Ko
1   University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea, Republic of
,
JH Yoon
2   Hanyang University College of Medicine, Seoul, Korea, Republic of
,
CM Cho
3   School of Medicine, Kyungpook National University, Daegu, Korea, Republic of
,
JH Cho
4   Gachon University College of Medicine, Incheon, Korea, Republic of
,
JH Choi
5   Dankook University of College of Medicine, Choenan, Korea, Republic of
,
DW Lee
6   Daegu Catholic University School of Medicine, Daegu, Korea, Republic of
,
SH Lee
7   Seoul National University College of Medicine, Seoul, Korea, Republic of
,
SB Yoon
8   Catholic University College of Medicine, Seoul, Korea, Republic of
,
SH Kim
9   Chonbuk National University College of Medicine, Jeonju, Korea, Republic of
,
TH Lee
10   Soonchunhyang University College of Medicine, Cheonan, Korea, Republic of
,
TH Kim
11   Wonkwang University School of Medicine, Iksan, Korea, Republic of
› Author Affiliations
Further Information

Publication History

Publication Date:
23 April 2020 (online)

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Aims Endoscopic ultrasound (EUS) has a high resolution and has shown its superiority to CT in the diagnosis of small pancreatic cancer. As a result, the role of EUS in the early detection of pancreatic cancer is attracting attention. The purpose of this study was to identify clinical and radiological characteristics of pancreatic cancer patients diagnosed with EUS but not found on CT.

Methods From January 2003 to April 2019, we had reviewed medical records of patients diagnosed with pancreatic cancer in 11 tertiary referral centers in Korea. The patients who’s pancreatic mass were not clearly seen on CT but identified in EUS were included in this study.

We analyzed clinical characteristics and radiological features of enrolled patients, and survival analysis was performed using the Kaplan-Meier method.

Results A total of 83 patients were enrolled. All of them underwent EUS and tumors were identified in all cases. Mean age was 64.1 (± 10.9) years old, 46 patients (55.4%) were male. The abnormal CT findings were as follows: main pancreatic duct dilatation (n = 61, 73.5%), double-duct sign

(n = 10, 12%), common bile duct dilatation (n = 9, 10.8%), splenic infarction (n = 1, 1.2%), pancreatitis (n = 1, 1.2%). Mean size of pancreatic tumor was 15.2 mm(± 4.8), and 90.4% was smaller than 2.0 cm. All but 4 patient underwent surgery. The final pathologic stages were as follows: stage IA (n = 31, 39.2%), stage IB (n = 8, 10.1%), stage IIA (n = 20, 25.3%), stage IIB (n = 17, 21.5 %), stage III (n = 2, 2.5%), Stage IV (n = 1, 1.4%). The median follow-up duration was 22.7 months (IQR 13.1–52.8).

The 5-year survival rate was 50.6% (95% C.I 38.2–66.9%), which was much higher than the previously known pancreatic cancer survival rate.

Conclusions When CT findings are indeterminate for pancreatic cancer, EUS should be considered due to its highly sensitive for detection of pancreatic cancer, especially when the tumor is smaller than 2.0 cm.