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CC BY-NC-ND 4.0 · Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery 2020; 39(03): 228-231
DOI: 10.1055/s-0040-1709985
Case Report | Relato de Caso

Spinal Cord Stimulation as a Treatment Option for Refractory Chemotherapy-Induced Peripheral Neuropathy: Case Report

Estimulação medular para tratamento da polineuropatia dolorosa induzida por quimioterapia: Relato de caso
Arthur Lopes 
1   Department of Neurology, Instituto do Câncer do Estado de São Paulo (Icesp), São Paulo, São Paulo, Brazil
2   Neurosurgery Medical Laboratory (LIM-62), Universdade de São Paulo (USP), São Paulo, Brazil
,
Kleber Duarte 
1   Department of Neurology, Instituto do Câncer do Estado de São Paulo (Icesp), São Paulo, São Paulo, Brazil
2   Neurosurgery Medical Laboratory (LIM-62), Universdade de São Paulo (USP), São Paulo, Brazil
3   Pain Center, DepartmentofNeurology, Universidade de São Paulo (USP), São Paulo, São Paulo, Brazil
,
Catarina Lins
1   Department of Neurology, Instituto do Câncer do Estado de São Paulo (Icesp), São Paulo, São Paulo, Brazil
,
Gabriel Kubota 
1   Department of Neurology, Instituto do Câncer do Estado de São Paulo (Icesp), São Paulo, São Paulo, Brazil
,
Valquíria Silva
2   Neurosurgery Medical Laboratory (LIM-62), Universdade de São Paulo (USP), São Paulo, Brazil
3   Pain Center, DepartmentofNeurology, Universidade de São Paulo (USP), São Paulo, São Paulo, Brazil
,
Ricardo Galhardoni 
2   Neurosurgery Medical Laboratory (LIM-62), Universdade de São Paulo (USP), São Paulo, Brazil
4   Department of Neurology, Faculdade de Medicina, Universidade Cidade de São Paulo (Unicid), São Paulo, São Paulo, Brazil
,
Luciana Mendes Bahia Menezes
1   Department of Neurology, Instituto do Câncer do Estado de São Paulo (Icesp), São Paulo, São Paulo, Brazil
,
Irina Raicher 
1   Department of Neurology, Instituto do Câncer do Estado de São Paulo (Icesp), São Paulo, São Paulo, Brazil
,
Manoel J. Teixeira 
1   Department of Neurology, Instituto do Câncer do Estado de São Paulo (Icesp), São Paulo, São Paulo, Brazil
2   Neurosurgery Medical Laboratory (LIM-62), Universdade de São Paulo (USP), São Paulo, Brazil
3   Pain Center, DepartmentofNeurology, Universidade de São Paulo (USP), São Paulo, São Paulo, Brazil
,
Daniel C. Andrade 
1   Department of Neurology, Instituto do Câncer do Estado de São Paulo (Icesp), São Paulo, São Paulo, Brazil
2   Neurosurgery Medical Laboratory (LIM-62), Universdade de São Paulo (USP), São Paulo, Brazil
3   Pain Center, DepartmentofNeurology, Universidade de São Paulo (USP), São Paulo, São Paulo, Brazil
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Abstract

Colorectal cancer is one of the most common oncological diseases. Chemotherapy is usually recommended as an adjuvant treatment for stage-II, -III, and -IV tumors. Approximately 10% of the patients develop neuropathic pain after chemotherapy, and they may remain refractory despite the administration of drugs that are commonly used to treat neuropathic pain. Spinal cord stimulation is a good treatment option for neuropathic pain of the lower limbs, and it should be trialed in patients with chemotherapy-induced peripheral neuropathy. We report the case of a patient with oxaliplatin-induced neuropathy and neuropathic pain refractory to oral medication who was successfully treated by spinal cord stimulation.

Resumo

O câncer colorretal é uma das neoplasias mais comuns na população em geral. A quimioterapia é habitualmente recomendada como tratamento adjuvante para tumores em estágios II, III e IV. Aproximadamente 10% dos pacientes irão desenvolver dor neuropática após a quimioterapia e eles podem se tornar refratários apesar da utilização de medicamentos para tratamento de dor neuropática. A estimulação medular espinhal é uma intervenção usualmente efetiva para alívio da dor neuropática em membros inferiores e deve ser testada em pacientes com neuropatia dolorosa induzida por quimioterapia. Nós descrevemos o caso de uma paciente portadora de neuropatia induzida por quimioterapia e dor neuropática refratária a medicações orais, a qual foi tratada de maneira bem-sucedida pela estimulação medular espinhal

Keywords

spinal cord stimulation - chemotherapy-induced peripheral neuropathy - colorectal cancer

Palavras-chave

estimulação medular espinhal - neuropatia periférica induzida por quimioterapia - câncer colorretal


Publication History

Received: 19 August 2019

Accepted: 10 March 2020

Article published online:
23 June 2020

© 2020. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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