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DOI: 10.1055/s-0040-1710973
Carbon ion therapy (C12) for primary treatment or in therapy of locally recurrent head and neck cancer
Background Technical innovations in radiotherapy could improve therapy of head and neck cancer significally: protons and C12 heavy ions reach a finite depth in the treated tissue defined by its kinetic energy. Therefore, sharp dose gradients are possible, additionally a higher biological effectiveness results. C12 therapy is used in tumors of paranasal sinuses, scull base and salivary glands and could improve overall survival and local control. In the therapy of tumor recurrence at the scull base long-term local control and improvement of symtoms is possible.
Methods After patient fixation CT-based target volume definition is made by image fusion of MRT an PET-CT-images. Radiation was applicated at Marburg Ion therapy center.
Patient 1 primary irradiation, cT4-salivary gland cancer of palate
Patient 2 re-irradiation of scull base metastasis of hypopharyngeal cancer
Results In the two cases local tumor control could be reached. Response must be assessed in the long term by CT-scanning because remission can take some month.
Conclusion Treatment with C12 heavy ions as efficient therapy in recurrent cancer of head and neck or in primary therapy of selected tumors completes recent therapy options.
Poster-PDF A-1564.PDF
Publication History
Article published online:
10 June 2020
© 2020. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).
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