DOI : 10.1055/s-00000036

Laryngo-Rhino-Otologie

Issue S 02 · Volume 99 · May 2020 DOI: 10.1055/s-010-48734

Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn
Abstract- und Posterband – 91. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn – Welche Qualität macht den Unterschied
Estrel Congress Center Berlin, 20.05 - 23.05.2020

Präsident: Prof. Dr. med. Andreas Dietz

Becker, S; Potthast, G; Gonser, P; Breuer, T; Wolpert, S; Löwenheim, H; Fröhlich, M; Ernst, B: Structured reporting of panendoscopies in otolaryngology – a preliminary study
Open Access
Böhm, F; Schuler, P; Doescher, J; Greve, J; Hoffmann, TK.; Theodoraki, Marie-Nicole: Primary small cell neuroendocrine carcinoma of the larynx: a case report
Open Access
Coordes, A; Boekert, R; Olze, H; Hofmann, V; Heiland, M; Piwonski, I; Stromberger, C: Carcinoma of unknown primary and the 8th Edition TNM Classification for Head and Neck Cancer
Open Access
Däxle, S; Mühlmeier, G; Tisch, M: Mucosal melanoma at the maxillar sinus– a rare disease
Open Access
Eckrich, J; Kugler, P; Welz, C; Strieth, S; Brieger, Jürgen; Becker, S: Effects of cold atmospheric plasma on solid tumors in ovo - An exploratory study using the HET Cam model
Open Access
Mansour, N; Knopf, A; Hofauer, B: Neck dissection Level II-IV – How we do it
Open Access
Scherzad, A; Stöth, M; Hagen, R; Hackenberg, S: Clinical and molecular analysis of sinunasal melanomas
Open Access
Schild, LR.; Dürselen, L; Böhm, F; Greve, J; Seywald, A; Boos, M; Hoffmann, TK.; Schuler, PJ.: Transoral videolaryngoscopic surgery of the larynx: Prototype with flexible surgical instruments provides appropriate visualization and accessibility
Open Access
Schuler, PJ.; Tews, D; Brunner, C; Laban, S; Döscher, J; Zinngrebe, J; Wabitsch, M; Debatin, Klaus-Michael; Möller, P; Hoffmann, TK.; Fischer-Posovszky, P: Cervical adipocytes and tumor cells interact in patients with head and neck cancer
Open Access
Schulz, F; Andrianopoulou, S; Schmitt, M; Lippert, B: Case Report: Skin adnexal carcinoma of the upper lip
Open Access
Trommer, J; Lörincz, BB.; Czilwik, T; Barth, C: Robotic-assisted use of the FAMM-flap to cover TORS-defects
Open Access
Zech, Henrike Barbara; Betz, CS; Kriegs, M; Köcher, S; Mansour, W; Möckelmann, N; Böttcher, A; Busch, Chia-Jung; Petersen, C; Rothkamm, K; Rieckmann, T: Ex-vivo slice cultures of tumor tissues confirm the DNA double-strand break repair defect of HPV-positive OPSCC and suggest a defect in the ATM-mediated DNA damage response
Open Access
Zhu, Z; Luo, D; Wollenberg, B; Feuerecker, B; Eiber, M; Pickhard, A: Treatment of PSMA-255-Actinium therapy induced xerostomia in patients with prostate cancer
Open Access
Affolter, A; Rong, C; Muller, MF.; Xiang, F; Jensen, A; Weichert, W; Major, G; Plinkert, PK.; Rotter, N; Heß, J: Adaptive ERK1/2 signalling as a response to HNSCC therapy
Open Access
Bast, H; Wilkat, M; Drees, R; Dünser, J; Brhel, M; Azoitei, N; Marienfeld, R; Frank, F; Ushmorov, A; Greve, J; Goldberg-Bockhorn, E; Theodoraki, Marie-Nicole; Döscher, J; Laban, S; Schuler, P; Hoffmann, TK.; Brunner, C: Adenosine receptor 2B activity promotes autonomous growth, migration as well as vascularization of head and neck squamous cell carcinoma cells
Open Access
Becker, B; Rieckmann, T; Betz, C; Busch, Chia-Jung; Droste, C; Clauditz, T; Münscher, A; Hagel, C: The predictive role of Axl and Gas6 in patients with squamous cell carcinoma of the head and neck
Open Access
Brand, M; Krüger, J; Greve, J; Theodoraki, Marie Nicole; Döscher, J; Laban, S; Schuler, PJ; Hoffmann, TK; Brunner, C: Characterization of adenosine receptor A2A (ADORA2A) mediated effects on the immunogenic tumor microenvironment (TME) in a head and neck squamous cell carcinoma (HNSCC) mouse model
Open Access
Brunner, C; Mahr, A; Bast, H; Drees, R; Dünser, J; Azoitei, N; Pscheid, R; Greve, J; Theodoraki, Marie-Nicole; Döscher, J; Laban, S; Schuler, PJ.; Hoffmann, TK.: Hif-1α-dependent expression of Adenosine Receptor 2B (ADORA2B) promotes autonomous growth, EMT as well as CSC enrichment in cultures of cells derived from head and neck squamous cell carcinomas
Open Access
Busch, Chia-Jung; von der Heyde, E; Welslau, M; Hahn, D; Bockmühl, U; Langer, C; Müller-Huesmann, H; Gauler, T; Waldenberger, D; Dietz, A: HANNA – Real-world data on effectiveness and safety of Nivolumab in patients with recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN) in Germany
Open Access
Deeg, N; Pfeiffer, J; Knopf, A; Becker, C; Ketterer, Manuel Christoph: Surgical nodal management in hypopharyngeal and laryngeal cancer
Open Access
Döscher, J; Minkenberg, P; Schuler, P; Laban, S; Hoffmann, TK.; Weissinger, S: Changes of immune checkpoint expression under conventional radiochemotherapy of head and neck carcinomas
Open Access
Eberle, F; Lautenschläger, S; Hauswald, H; Jensen, A; Dumke, C; Engenhart-Cabillic, R: Carbonion-boost (C12) followed by radiochemotherapy with photons as organ preservingProcedure for SCC of the Nasal Vestibule
Open Access
Eyth, Christian Peter; Hansen, S; Bruderek, K; Schirrmann, R; Petra, A; Wey, K; Kollenda, S; Hackel, A; Vollmer, S; Lang, S; Epple, M; Brandau, S: Cetuximab-conjugated Nanoparticles as drug delivery systems. Distribution and biological effects on epithelial and mesenchymal cells in the head and neck area
Open Access
Fazel, A; Quabius, Elgar Susanne; Laudien, M; Hoffmann, M: HPV-DNA in sputum cannot be used to distinguish between an infection or a contamination
Open Access
Foerster, Y; Diensthuber, M; Balster, S; Gabrielpillai, J; Petzold, H; Wagenblast, J; Stöver, T; Geißler, C: Neurotrophin receptors - prognostic markers and therapeutic targets for HNSCC?
Open Access
Gehrt, F; Rudhart, Stefan Alexander; Geisthoff, U; Birk, R; Stuck, Boris Alexander; Hoch, S; Thangavelu, K: Value of CYFRA 21-1 as a tumor marker in the context of treatment for advanced laryngeal- and hypopharyngeal cancer
Open Access
Gostian, Antoniu - Oreste; Hecht, M; Eckstein, M; Rutzner, S; von der Grün, J; Illmer, T; Hautmann, M; Brunner, T; Laban, S; Klautke, G; Tamaskovics, B; Frey, B; Hartmann, A; Rödel, C; Budach, W; Gaipl, U; Fitkau, R; Iro, H: First-line treatment of locally advanced HNSCC with double checkpoint inhibition and radiotherapy based on CD8+ T cell infiltration.
Open Access
Haase, MW.; Langer, Jörg: Rare endonasal tumors
Open Access
Hadas, S; Feigl, K; Wollenberg, B; Pickhard, A; Buchberger, M: Head and neck tumor- patient follow -up care – signs and symptoms to look for
Open Access
Hess, J; Feng, B; Shen, Y; Huang, Q; Pastor Hostench, X; Bieg, M; Plath, M; Huber, P; Ishaque, N; Eils, R; Freier, K; Weichert, W; Zaoui, K: Genetic and epigenetic landscape of the molecular immuno-signature in HNSCC
Open Access
Hofmann, L; Brunner, C; Schuler, P; Hoffmann, T; Laban, S; Theodoraki, Marie-Nicole: Characterization of circulating exosomes as biomarkers for therapy monitoring in Head and Neck cancer (HNSCC) patients
Open Access
Idel, C; Krupar, R; Watermann, C; Pasternack, H; Ribbat-Idel, J; Perner, S; Wollenberg, B: Primary and local recurrent head and neck squamous cell carcinomas are strikingly different regarding their immune microenvironment
Open Access
Jakobi, Paul Joseph; Hackenberg, S; Ehrmann-Müller, Désirée; Hagen, R: Cervical metastasis of male breast cancer
Open Access
Jira, D; Ganser, D; Rudelius, M; Wollenberg, B; Buchberger, M; Pickhard, A: Tumor heterogeneity of immunoactive cells as a possible prognostic marker in HNSCC
Open Access
Kemper, M; Olesch, Falk-Tony; Schneider, M; Lehnert, R; Linge, A; Haim, D; Lauer, Günter; Gudziol, V; Löck, S; Baumann, M; Barreton, G; Krause, M; Zahnert, T: Retrospective und prospective biomarker studies in early stage HNSCC- first clinical results-
Open Access
Knopf, A; Pickhard, A; Fritsche, K; El Shabrawi, K: TIMP1 as molecular marker in distant metastatic outgrowth
Open Access
Kühn, Jan Philipp; Bochen, F; Schick, B; Wagner, M; Bohle, Rainer Maria; Smola, S; Linxweiler, M: Podoplanin expression in lymphogenic metastases of head and neck cancer
Open Access
Lauer, Anna-Christina; Khoo, Andre Boo Shern; Goon, Patrick Kin Young; Goon, Peter Kin Cho; Sudhoff, H: Comparative analysis of tumor growth of periocular und non-periocular basal cell carcinomas
Open Access
Linxweiler, M; Schmid, W; Körner, S; Bochen, F; Wemmert, S; Smola, S; Lohse, S; Wagner, M; Schick, B: HPV status as predictive biomarker in head and neck cancer – which method fits the best for outcome prediction?
Open Access
Ludwig, S; Rist, M; Theodoraki, Marie-Nicole; Giebel, B; Lang, S; Rotter, N; Jablonska, J: Stage-Dependent Exosomal Protein Expression of PD-L1 and FasL in Head and Neck Cancer (HNC) Patients
Open Access
Lübbers, K; Pavlychenko, M; Wiegand, S; Dietz, A; Zebralla, V; Wichmann, G: Age-dependant outcome in EXTREME-regimen – a factor to consider in palliative chemotherapy?
Open Access
Messow, Helen Josephine; Mittmann, P; Decker, L; Seidl, R: Simultaneous appearance of subcranial intrajugulare Glomus tumors and hemangioma
Open Access
Mytilineos, D; Fürst, D; Tsamadou, C; Mytilineos, J; Theodoraki, Marie-Nicole; Döscher, J; Schuler, P; Brunner, C; Hoffmann, T; Laban, S: HLA-Allele-frequencies differ between patiens with head neck cancer (HNSCC) and healthy controls and between HPV-positiv and HPV-negative HNSCC patients
Open Access
Nguyen, J; Aderhold, C; Lammert, A; Rotter, N; Hörner, C; Schell, A: Initial manifestation of a diffus large B-Cell-Lymphoma of the paranasal sinuses
Open Access
Oberste, M; Göttker, Philipp Donatus; Simon, F; Rudack, C: Role of PD-L1 expression in sinonasal cancer
Open Access
Pilavakis, Y; Beutner, D; Leu, M; Bremmer, F; Netzer, C; Rödel, R: Head and neck carcinoma of unknown primary: diagnosis, management and treatment outcomes in 102 patients
Open Access
Pöttler, M; Holler, A; Eckstein, M; Haderlein, M; Rappl, A; Alexiou, C: Extramedullary PlasmacytomaTumor Occurrence and Therapeutic Concepts – a follow-up
Open Access
Priese, J; Hums, Anna-Bawany; Erler, T; Jansen, L; Dürst, M; Schmitz, M; Hansel, A; Guntinas-Lichius, O: Promising epigenetic biomarkers for improved detection of head and neck cancer by quantitative real time multiplex PCR in saliva samples
Open Access
Reichel, C; Mittmann, L; Schaubächer, J; Hennel, R; Zuchtriegel, G; Canis, M; Gires, O; Krombach, F; Holdt, L; Brandau, S; Vogl, T; Lauber, K; Uhl, B: Excessive biological ageing of circulating neutrophils in HNSCC promotes tumor progression
Open Access
Scheckenbach, K; Bister, A; Schulte, E; Hanenberg, H; Wiek, C; Wagenmann, M; Schipper, Jörg; Haist, C: Development of an EGFR-targeted CAR T-cell immunotherapy in head and neck cancer
Open Access
Schmidl, B; Siegl, M; Winter, C; Boxberg, M; Jira, D; Heiser, C; Pickhard, A; Wollenberg, B; Wirth, M: Characterizing the role of NOTCH1 for the Squamous-Cell-Carcinoma of the Head-and-Neck
Open Access
Schulte, E; Scheckenbach, K; Haist, C; Bister, A; Hanenberg, H; Wiek, C: CD44v6-targeted CAR T-cell therapy for head and neck squamous cell carcinoma
Open Access
Shahpasand, S; Beutner, D: NUT midline carcinoma - a Case Report
Open Access
Siegl, M; Seidl, C; Bruchertseifer, F; Morgenstern, A; Zissler, U; Multhoff, G; Wollenberg, B; Pickhard, A: In-vitro targeted alpha-particle therapy (TAT) with 213Bi-Cetuximab outperforms X-Ray irradiation independent of HPV status of HNSCC cell lines
Open Access
Strüder, D; Momper, T; Irmscher, N; Liese, J; Schraven, S; Zimpfer, A; Junghanß, C; Frerich, B; Mlynski, R; Maletzki, C: Setup of a head and neck cancer biobank and patient-derived xenografts - Differential engraftment of surgical specimens and endoscopic biopsies
Open Access
Tenschert, E; Kern, J; Jungbauer, F; Rotter, N; Lammert, A: Establishment of a 3D tumor model – challenges and advantages of co-cultured spheroids
Open Access
Theodoraki, Marie-Nicole; Schuler, PS.; Laban, S; Brunner, C; Hoffmann, TK.; Whiteside, TL.: CD44v3 as a Biomarker of Tumor-derived Exosomes in Plasma from Head and Neck Squamous Cell Carcinoma Patients
Open Access
Ugele, I; Singer, K; Wehrstein, M; Symeou, L; Dettmer, K; Kapsreiter, M; Bohr, C; Kreutz, M: Immunological and metabolic characterization in HNSCC
Open Access
Uhl, B; Braun, C; Haring, F; Dominik, J; Mittmann, L; Canis, M; Reichel, C: Protection of the glycocalyx reduces myeloid leukocyte trafficking and tumor progression in experimental HNSCC
Open Access
Vahl, Julius Malte; Döscher, J; Laban, S; Theodoraki, Marie Nicole; Greve, J; Hoffmann, TK; Schuler, PJ: Influence of the clinical care of head and neck cancer patients by the distance to the clinical center
Open Access
von Fournier, A; Scherzad, A; Hackenberg, S; Hagen, R: Metastastatic basal cell carcinoma – A case report
Open Access
Wald, T; Siemert, J; Kolb, M; Dietz, A; Zebralla, V; Fest, S; Wiegand, S; Wichmann, G: Comorbidity impairs tumor-specific survival of patients with advanced squamous cell carcinoma of the head and neck-region
Open Access
Weiland, T; Tomazic, Peter Valentin; Wolf, A; Brcic, L; Pondorfer-Schäfer, P; Vasicek, S; Holzmeister, C; Kiss, P; Graupp, M; Thurnher, D: DRH1 – Evaluating a blood-based marker for HPV16-induced tumors
Open Access
Widmann, M; Gires, O; Baumeister, P; Canis, M: Second and Third Harmonic Generation Imaging of Head and Neck Cancer
Open Access
Wilhelm, C; Grein, H; Hackenberg, S; Kleinsasser, N; Scherzad, A: Proliferation of epithelial tumor cells in presence of human mesenchymal stem cells
Open Access
Wirth, M; Vossenkämper, Kim-Aylin; Boxberg, M; Feigl, K; Wirth, M; Johnson, F; Siegl, M; Wollenberg, B; Pickhard, A: Are there immunohistological differences between cervical CUP syndrome and oropharyngeal carcinoma?
Open Access
Zhi, Y; Serfling, S; Buck, A; Gerhard-Hartmann, E; Scherzad, A; Hagen, R; Hackenberg, S: Investigation of head and neck tumors with 68Ga-FAPI, the new radiotracer
Open Access
Betz, CS.; Laban, S; Wittekindt, C; Stromberger, C; Tribius, S; Klußmann, Jens Peter; Budach, V; Münscher, A; Busch, Chia-Jung: Trial in Progress: Comparative Effectiveness Trial of Transoral Head and Neck Surgery followed by adjuvant Radio(chemo)therapy versus primary Radiochemotherapy for Oropharyngeal Cancer (TopROC)
Open Access
Fehn, A; Ezic, J; Brunner, C; Theodoraki, Marie-Nicole; Döscher, J; Schuler, P; Greve, J; Marienfeld, R; Koretz, K; Hoffmann, T; Laban, S: Abundance of immune checkpoint molecules and their ligands in Oropharyngeal Squamous cell carcinoma (OPSCC) depends on HPV status and can be modulated by demethylation.
Open Access
Haider, Stefan Philipp; Mahajan, A; Zeevi, T; Forghani, R; Kann, B; Judson, BL.; Burtness, B; Sharaf, K; Reichel, C; Baumeister, P; Payabvash, S: Devising novel imaging biomarkers for Human Papillomavirus (HPV) status in oropharyngeal squamous cell carcinoma (OPSCC): applying radiomics and machine learning algorithms
Open Access
Hoffmann, Anna Sophie; Busch, Chia-Jung; Rieckmann, T; Betz, C; Jagodzinski, A; Viarisio, D; Pawlita, M; Waterboer, T: Analysis of HPV 16 early protein antibodies and identification of patients at high risk for HPV-driven oropharyngeal cancer in the prospective cohort of the Hamburg City Health Study
Open Access
Hoffmann, M; Quabius, Elgar Susanne; Brandt, P; Heinrichs, A; Kühnel, André; Laudien, M; Mlynski, R; Hoppe, F; Ambrosch, P: HPV-DNA and -RNA in tonsils, sputum and tonsillar swabs of patients with tonsillar hyperplasia (H), chronic tonsillitis (CT) and tonsillar squamous cell carcinomas (TSCC)
Open Access
Künzel, J; Beltz, Anna Katharina; Zimmer, S; Stauber, RH.: Extracapsular growth in HPV positive oropharyngeal cancer
Open Access
Netzer, C; Witte Paz, H; Weigert, A; Beutner, D: Examination of lymphatic metastasis of oropharyngeal carcinomas by Phenoptics
Open Access
Pondorfer-Schäfer, P; Vasicek, Sarah Marvis; Karakitsiou, M; Weiland, T; Graupp, M; Wolf, A; Strasser, A; Moser, U; Holzmeister, C; Wild, D; Brcic, L; Thurnher, D: C-reactive protein as prognostic marker in patients with p16-negative vs. p16-positive oropharyngeal squamous cell carcinoma
Open Access
Rudhart, Stefan Alexander; Langen, P; Thangavelu, K; Geisthoff, U; Birk, R; Stuck, Boris Alexander; Hoch, S: Clinical impact of CYFRA 21-1 as a marker for treatment failure in patients with oropharyngeal cancer and primary radio(chemo)therapy
Open Access
Stöhr, Matthäus; Mehlhorn, S; Oeser, A; Dietz, A; Gaebel, J; Cypko, MA.: Development of a treatment supporting system for oropharynxgeal carcinoma
Open Access
Weiss, BG.; Anczykowski, Mahalia Zoe; Canis, M; Ihler, F; Kitz, J; Jakob, M: Prognostic impact of additional HPV-typing in p16-stratified advanced oropharyngeal squamous cell carcinoma
Open Access
Würdemann, N; Siefer, O; Pucknat, V; Klußmann, Jens Peter; Hübbers, C: Analysis of TP63 splice variants in OPSCC in accordance to HPV status
Open Access
Jakob, M; Mattes, L; Canis, M; Weiss, BG.: Importance of microRNAs as potential biomarkers for oral carcinoma
Open Access
Obermüller, T; Hofmann, Veit Maria; von Bernstorff, M; Pudszuhn, A; Prigge, Elena-Sophie: Meta-Analysis on the diagnostic significance of p16INK4A and HR-HPV DNA in identifying HPV-driven oral cavity cancer
Open Access