Download PDF
CC BY-NC-ND 4.0 · Int Arch Otorhinolaryngol 2021; 25(03): e463-e470
DOI: 10.1055/s-0040-1714131
Systematic Review

Vertiginous Episodes in Menière Disease following Transmyringeal Ventilation Tube Insertion: A Systematic Review on the Current State of Evidence

Casper Grønlund 
1   Department of Ear, Nose, Throat and Maxillofacial Surgery, Zealand University Hospital, Koege, Denmark
,
Louise Devantier 
2   Department of Oto-Rhino-Laryngology, Regional Hospital West Jutland, Holstebro, Denmark
3   Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
,
Henriette Edemann Callesen 
4   The Danish Health Authority, Copenhagen, Denmark
,
Dan Dupont Hougaard 
5   Department of Otolaryngology, Head & Neck Surgery and Audiology, Aalborg University Hospital, Aalborg, Denmark
,
Mina Nicole Händel 
4   The Danish Health Authority, Copenhagen, Denmark
6   The Parker Institute, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark
,
Jesper Hvass Schmidt 
7   Department of ORL, Head and Neck Surgery and Audiology, Odense University Hospital, Odense C, Denmark
8   Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark
,
Frank Liviu-Adelin Guldfred
9   Ear, Nose and Throat Clinic, Faxe, Denmark
,
Bjarki Ditlev Djurhuus 
1   Department of Ear, Nose, Throat and Maxillofacial Surgery, Zealand University Hospital, Koege, Denmark
› Author Affiliations
› Further Information
   Permissions and Reprints

Abstract

Introduction Menière disease (MD) is a disorder characterized by episodes of vertigo, sensorineural hearing loss, tinnitus and aural fullness.

Objectives To assess the effect of ventilation tube insertion (VTI) on vertiginous episodes in patients (≥ 18 years old) with MD.

Data Synthesis A systematic literature search on randomized clinical trials (RCTs), nonrandomized trials and other systematic reviews was performed. The Grades of Recommendation, Assessment, Development, and Evaluation (GRADE) approach was used to assess the overall certainty of evidence.

Two RCTs and four nonrandomized studies were identified. Data extraction was only possible for one RCT. Results showed that the number of patients with no vertigo attacks significantly increased following active treatment (relative risk 1.52; [95% confidence interval: 1.19–1.94]). The quality of evidence was rated as low. None of the nonrandomized trials included a proper control group, which hindered data extraction and quality assessment.

Conclusion There are currently no RCTs that specifically assess the efficacy of VTI in patients with MD. Current limited data suggest a considerable positive effect on the number of vertiginous episodes in patients with MD. However, due to poor evidence, a fluctuating course and a substantial placebo-effect associated with MD-treatment, no solid conclusion(s) regarding the efficacy of VTI can be made. There is a need for high-quality RCTs.

Keywords

ventilation tube insertion - Meniere disease - vertigo - dizziness - hearing

Final Comments

There are no RCTs that directly assess the efficacy of VTI on the number of vertiginous attacks in patients with definite or probable MD. Current data are suggestive of a considerable positive effect on the number of vertiginous attacks in patients with MD. However, due to poor quality data, the fluctuating course, and a substantial placebo effect associated with MD treatment, no solid conclusion(s) regarding the efficacy of VTI in patients with MD can be made. There is a need for high-quality RCTs on this matter.


Trial Registration Number

The protocol for the manuscript is registered in PROSPERO. Registration number: CRD42019134851, acceptance date: July 8, 2019. The present review was performed in accordance with the guidelines for systematic reviews and meta-analyses and Preferred Reported Items for Systemtic Reviews and Meta-analyses (PRISMA).




Publication History

Received: 14 January 2020

Accepted: 05 June 2020

Article published online:
30 September 2020

© 2020. Fundação Otorrinolaringologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

Thieme Revinter Publicações Ltda.
Rua do Matoso 170, Rio de Janeiro, RJ, CEP 20270-135, Brazil

 

  • References

  • 1 Espinosa-Sanchez JM, Lopez-Escamez JA. Menière's disease. Handb Clin Neurol 2016; 137: 257-277
    CrossrefPubMedGoogle Scholar
  • 2 Lopez-Escamez JA, Carey J, Chung WH. et al; Classification Committee of the Barany Society; Japan Society for Equilibrium Research; European Academy of Otology and Neurotology (EAONO); Equilibrium Committee of the American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS); Korean Balance Society. Diagnostic criteria for Menière's disease. J Vestib Res 2015; 25 (01) 1-7
    CrossrefPubMedGoogle Scholar
  • 3 Coelho DH, Lalwani AK. Medical management of Ménière's disease. Laryngoscope 2008; 118 (06) 1099-1108
    CrossrefPubMedGoogle Scholar
  • 4 Wu V, Sykes EA, Beyea MM, Simpson MTW, Beyea JA. Approach to Ménière disease management. Can Fam Physician 2019; 65 (07) 463-467
    PubMedGoogle Scholar
  • 5 Tumarkin A. Thoughts on the treatment of labyrinthopathy. J Laryngol Otol 1966; 80 (10) 1041-1053
    CrossrefPubMedGoogle Scholar
  • 6 Lall M. Ménière's disease and the grommet (a survey of its therapeutic effects). J Laryngol Otol 1969; 83 (08) 787-791
    CrossrefPubMedGoogle Scholar
  • 7 Cinnamond MJ. Eustachian tube function in Menière's disease. J Laryngol Otol 1975; 89 (01) 57-61
    CrossrefPubMedGoogle Scholar
  • 8 Hall MC, Brackmann DE. Eustachian tube blockage and Meniere's disease. Arch Otolaryngol 1977; 103 (06) 355-357
    CrossrefPubMedGoogle Scholar
  • 9 Montandon P, Guillemin P, Häusler R. Prevention of vertigo in Ménière's syndrome by means of transtympanic ventilation tubes. ORL J Otorhinolaryngol Relat Spec 1988; 50 (06) 377-381
    CrossrefPubMedGoogle Scholar
  • 10 Authorities TNH. Nasjonale retningslinjer for utredning, behandling og oppfølging av pasienter med Menières sykdom. 2016
    PubMed
  • 11 Ménières sygdom, morbus Meniere. Dansk selskab for Vestibulogi under DSOHH2016.
  • 12 Guyatt GH, Oxman AD, Schünemann HJ, Tugwell P, Knottnerus A. GRADE guidelines: a new series of articles in the Journal of Clinical Epidemiology. J Clin Epidemiol 2011; 64 (04) 380-382
    CrossrefPubMedGoogle Scholar
  • 13 Moher D, Shamseer L, Clarke M. et al; PRISMA-P Group. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Syst Rev 2015; 4: 1
    CrossrefPubMedGoogle Scholar
  • 14 Guyatt GH, Oxman AD, Kunz R. et al. GRADE guidelines: 2. Framing the question and deciding on important outcomes. J Clin Epidemiol 2011; 64 (04) 395-400
    CrossrefPubMedGoogle Scholar
  • 15 Committee on Hearing and Equilibrium guidelines for the diagnosis and evaluation of therapy in Menière's disease. American Academy of Otolaryngology-Head and Neck Foundation, Inc. Otolaryngol Head Neck Surg 1995; 113 (03) 181-185
    CrossrefPubMedGoogle Scholar
  • 16 Marchbanks RJ, Reid A. Cochlear and cerebrospinal fluid pressure: their inter-relationship and control mechanisms. Br J Audiol 1990; 24 (03) 179-187
    CrossrefPubMedGoogle Scholar
  • 17 Shea BJ, Grimshaw JM, Wells GA. et al. Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews. BMC Med Res Methodol 2007; 7: 10
    CrossrefPubMedGoogle Scholar
  • 18 Higgins JP, Altman DG, Gøtzsche PC. et al; Cochrane Bias Methods Group; Cochrane Statistical Methods Group. The Cochrane Collaboration's tool for assessing risk of bias in randomised trials. BMJ 2011; 343: d5928
    CrossrefPubMedGoogle Scholar
  • 19 Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med 2002; 21 (11) 1539-1558
    CrossrefPubMedGoogle Scholar
  • 20 Mantel N, Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 1959; 22 (04) 719-748
    PubMedGoogle Scholar
  • 21 DerSimonian R, Laird N. Meta-analysis in clinical trials revisited. Contemp Clin Trials 2015; 45 (Pt A): 139-145
    CrossrefPubMedGoogle Scholar
  • 22 Review Manager (RevMan). (Computer program) Copenhagen: The Nordic Cochrane Centre, Cochrane Collaboration; 2014
    PubMed
  • 23 Sugawara K, Kitamura K, Ishida T, Sejima T. Insertion of tympanic ventilation tubes as a treating modality for patients with Meniere's disease: a short- and long-term follow-up study in seven cases. Auris Nasus Larynx 2003; 30 (01) 25-28
    CrossrefPubMedGoogle Scholar
  • 24 Park JJ, Chen YS, Westhofen M. Meniere's disease and middle ear pressure: vestibular function after transtympanic tube placement. Acta Otolaryngol 2009; 129 (12) 1408-1413
    CrossrefPubMedGoogle Scholar
  • 25 Ogawa Y, Otsuka K, Hagiwara A. et al. Clinical study of tympanostomy tube placement for patients with intractable Ménière's disease. J Laryngol Otol 2015; 129 (02) 120-125
    CrossrefPubMedGoogle Scholar
  • 26 Barbara M, Consagra C, Monini S. et al. Local pressure protocol, including Meniett, in the treatment of Ménière's disease: short-term results during the active stage. Acta Otolaryngol 2001; 121 (08) 939-944
    CrossrefPubMedGoogle Scholar
  • 27 Kitahara T, Okamoto H, Fukushima M. et al. A Two-Year Randomized Trial of Interventions to Decrease Stress Hormone Vasopressin Production in Patients with Meniere's Disease-A Pilot Study. PLoS One 2016; 11 (06) e0158309
    CrossrefPubMedGoogle Scholar
  • 28 Russo FY, Nguyen Y, De Seta D. et al. Meniett device in meniere disease: Randomized, double-blind, placebo-controlled multicenter trial. Laryngoscope 2017; 127 (02) 470-475
    CrossrefPubMedGoogle Scholar
  • 29 Yamane T. [Developmental Disorder Parenting Stressor Index (DDPSI): reliability and validity]. Shinrigaku Kenkyu 2013; 83 (06) 556-565
    CrossrefPubMedGoogle Scholar
  • 30 Silverstein H, Smouha E, Jones R. Natural history vs. surgery for Menière's disease. Otolaryngol Head Neck Surg 1989; 100 (01) 6-16
    CrossrefPubMedGoogle Scholar
  • 31 Sevilla C, Goody J, Baguley DM, Kasbekar AV. Aural fullness and transtympanic ventilation tubes in Ménière's disease: a scoping review. J Laryngol Otol 2019; 133 (06) 450-456
    CrossrefPubMedGoogle Scholar
  • 32 Kitahara T, Doi K, Maekawa C. et al. Meniere's attacks occur in the inner ear with excessive vasopressin type-2 receptors. J Neuroendocrinol 2008; 20 (12) 1295-1300
    CrossrefPubMedGoogle Scholar
  • 33 Maekawa C, Kitahara T, Kizawa K. et al. Expression and translocation of aquaporin-2 in the endolymphatic sac in patients with Meniere's disease. J Neuroendocrinol 2010; 22 (11) 1157-1164
    CrossrefPubMedGoogle Scholar
  • 34 Brattmo M, Tideholm B, Carlborg B. Inadequate opening capacity of the eustachian tube in Meniere's disease. Acta Otolaryngol 2012; 132 (03) 255-260
    CrossrefPubMedGoogle Scholar
  • 35 Park JJ, Luedeke I, Luecke K, Emmerling O, Westhofen M. Eustachian tube function in patients with inner ear disorders. European archives of oto-rhino-laryngology: official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS): affiliated with the German Society for Oto-Rhino-Laryngology -. Head Neck Surg 2013; 270 (05) 1615-1621
    Google Scholar
  • 36 Ivarsson A, Pedersen K. Volume-pressure properties of round and oval windows. A quantitative study on human temporal bone. Acta Otolaryngol 1977; 84 (1-2): 38-43
    CrossrefPubMedGoogle Scholar