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CC BY-NC-ND 4.0 · AJP Rep 2021; 11(01): e5-e14
DOI: 10.1055/s-0040-1721668
Case Report

Risk of Early Birth among Women with a Urinary Tract Infection: A Retrospective Cohort Study

Autoren

  • Rebecca J. Baer 

    1   Department of Pediatrics, University of California San Diego, La Jolla, California
    2   Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, California
    3   The California Preterm Birth Initiative, University of California San Francisco, San Francisco, California

  • Nichole Nidey

    4   Department of Epidemiology, University of Iowa, Iowa City, Iowa

  • Gretchen Bandoli

    1   Department of Pediatrics, University of California San Diego, La Jolla, California

  • Brittany D. Chambers

    3   The California Preterm Birth Initiative, University of California San Francisco, San Francisco, California
    5   Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California

  • Christina D. Chambers

    1   Department of Pediatrics, University of California San Diego, La Jolla, California

  • Sky Feuer

    2   Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, California
    3   The California Preterm Birth Initiative, University of California San Francisco, San Francisco, California

  • Deborah Karasek

    2   Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, California
    3   The California Preterm Birth Initiative, University of California San Francisco, San Francisco, California

  • Scott P. Oltman

    3   The California Preterm Birth Initiative, University of California San Francisco, San Francisco, California
    5   Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California

  • Larry Rand

    2   Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, California
    3   The California Preterm Birth Initiative, University of California San Francisco, San Francisco, California

  • Kelli K. Ryckman

    4   Department of Epidemiology, University of Iowa, Iowa City, Iowa
    6   Department of Pediatrics, University of Iowa, Iowa City, Iowa

  • Laura L. Jelliffe-Pawlowski

    3   The California Preterm Birth Initiative, University of California San Francisco, San Francisco, California
    5   Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California
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Abstract

Objective The aim of the study is to evaluate the risk of preterm birth (PTB, <37 weeks) and early term (37 and 38 weeks) birth among women with an emergency department (ED) visit or hospitalization with a urinary tract infection (UTI) by trimester of pregnancy.

Methods The primary sample was selected from births in California between 2011 and 2017. UTIs were identified from the ED or hospital discharge records. Risk of PTB, by subtype, and early term birth were evaluated by trimester of pregnancy and by type of visit using log-linear regression. Risk ratios were adjusted for maternal factors. Antibiotic usage was examined in a population of privately insured women from Iowa.

Results Women with a UTI during pregnancy were at elevated risk of a birth <32 weeks, 32 to 36 weeks, and 37 to 38 weeks (adjusted risk ratios [aRRs] 1.1–1.4). Of the women with a diagnostic code for multiple bacterial species, 28.8% had a PTB. A UTI diagnosis elevated risk of PTB regardless of antibiotic treatment (aRR 1.4 for treated, aRR 1.5 for untreated).

Conclusion UTIs are associated with early birth. This association is present regardless of the trimester of pregnancy, type of PTB, and antibiotic treatment.

Keywords

preterm birth - early term birth - urinary tract infection - bacterial species - trimester of infection

Supplementary Material



Publikationsverlauf

Eingereicht: 01. April 2020

Angenommen: 02. Oktober 2020

Artikel online veröffentlicht:
13. Januar 2021

© 2021. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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