Journal of Pediatric Neurology
DOI: 10.1055/s-0040-1721827
Case Report

Primary Headache Associated with Sexual Activity in Adolescents: Illustrative Cases

1  Faculty of Medicine, Imperial College London, London, United Kingdom
David A. Rothner
2  Department of Pediatric Neurology, Cleveland Clinic, Cleveland, Ohio, United States
› Author Affiliations
Funding None.


Primary headache associated with sexual activity (PHASA) is well described in adults, but reports in adolescents are lacking. PHASA is likely underreported in adolescents. A delay in or an absence of timely and adequate treatment has the potential to negatively impact normal adolescent psychosexual development. Physicians should consider this disorder in adolescents presenting with headaches, and understand the characteristics, diagnosis, and treatment. We report two cases of PHASA in adolescents and review the epidemiology, presentation, and management.

Publication History

Received: 10 October 2020

Accepted: 20 November 2020

Publication Date:
13 January 2021 (online)

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