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Journal of Pediatric Neurology 2022; 20(05): 330-335
DOI: 10.1055/s-0041-1728700
Case Report

Critical Illness Myopathy in a Child with SARS-CoV-2 Infection

María Jiménez-Legido‡   *
1   Department of Neuropediatrics, Hospital Infantil Universitario Niño Jesús, Madrid, Spain
,
Víctor Soto-Insuga‡   *
1   Department of Neuropediatrics, Hospital Infantil Universitario Niño Jesús, Madrid, Spain
,
Manuel Luján-Bonete
2   Department of Neurophysiology, Hospital Infantil Universitario Niño Jesús, Madrid, Spain
,
Verónica Cantarín-Extremera
1   Department of Neuropediatrics, Hospital Infantil Universitario Niño Jesús, Madrid, Spain
3   Clinical Group linked (GCV14/ER/6) affiliated with the Networked Biomedical Research Centre for rare Diseases (CIBERER), Carlos III Health Institute, Madrid, Spain
,
Beatriz Bernardino-Cuesta
1   Department of Neuropediatrics, Hospital Infantil Universitario Niño Jesús, Madrid, Spain
,
David Mansilla-Lozano
2   Department of Neurophysiology, Hospital Infantil Universitario Niño Jesús, Madrid, Spain
,
Inés Leoz-Gordillo
4   Pediatric Intensive Care Unit, Hospital Infantil Universitario Niño Jesús, Madrid, Spain
,
Serafín Rodríguez-Palero
5   Pediatric Rehabilitation Department, Hospital Infantil Universitario Niño Jesús, Madrid, Spain
,
Silvia Buendía-Martínez
6   Clinical Biochemist, Hospital Infantil Universitario Niño Jesús, Madrid, Spain
,
Anna Duat-Rodríguez
1   Department of Neuropediatrics, Hospital Infantil Universitario Niño Jesús, Madrid, Spain
,
María Luz Ruíz-Falcó-Rojas
1   Department of Neuropediatrics, Hospital Infantil Universitario Niño Jesús, Madrid, Spain
3   Clinical Group linked (GCV14/ER/6) affiliated with the Networked Biomedical Research Centre for rare Diseases (CIBERER), Carlos III Health Institute, Madrid, Spain
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Abstract

A variety of symptoms affecting the nervous system and/or skeletal muscle have been described during the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic. Though largely unexplored in children, intensive care unit-acquired weakness (ICU-AW) is associated with significant comorbidities. No previous pediatric cases of ICU-AW associated with coronavirus disease 2019 have been reported. A 12-year-old boy with SARS-CoV-2 infection developed systemic inflammatory response syndrome. Seven days later, he developed severe muscle weakness, with a creatine kinase level of 402 U/L. Nerve conduction studies and electromyography revealed a myopathic pattern. Severe pediatric cases of SARS-CoV-2 infection may develop ICU-AW. Early diagnosis and rehabilitation may decrease comorbidity and improve quality of life.

Keywords

SARS-CoV-2 - COVID-19 - critical illness myopathy - intensive care unit-acquired weakness - rehabilitation

* Both authors contributed equally to this study.




Publication History

Received: 17 October 2020

Accepted: 03 March 2021

Article published online:
21 May 2021

© 2021. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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