Digestive Disease Interventions 2021; 05(02): 090-092
DOI: 10.1055/s-0041-1729944
Review Article

Radioembolization for Metastatic Colorectal Cancer

Authors

  • David Guez

    1   Division of Interventional Radiology, Department of Radiology, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts
  • Patrick D. Sutphin

    2   Division of Interventional Radiology, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
  • Suvranu Ganguli

    1   Division of Interventional Radiology, Department of Radiology, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts

Abstract

The liver is the most common site of metastatic disease in colorectal cancer, and, in the setting of liver-dominant disease, a chief contributor to mortality. Chemotherapy is the backbone of treatment for metastatic colorectal cancer; however, the duration of response is limited and resistance to therapy inevitably develops. Radioembolization represents a targeted treatment to the liver which has been studied in first-line, second-line, and in salvage treatment. Therapeutic rationale, outcomes, and prognostic indicators are presented in this systematic review article.



Publication History

Received: 07 January 2021

Accepted: 01 April 2021

Article published online:
17 May 2021

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