Journal of Pediatric Neurology 2022; 20(03): 231-234
DOI: 10.1055/s-0041-1733937
Case Report

Multifocal Calvarial Infarction with Epidural Hemorrhage in a Patient with Sickle Cell Vaso-Occlusive Crisis: A Case Report

1   Department of Diagnostic Radiology, Cooper University Hospital, Camden, New Jersey, United States
,
Thomas Presenza
1   Department of Diagnostic Radiology, Cooper University Hospital, Camden, New Jersey, United States
,
Emily Scattergood
1   Department of Diagnostic Radiology, Cooper University Hospital, Camden, New Jersey, United States
,
Jason Solomon
1   Department of Diagnostic Radiology, Cooper University Hospital, Camden, New Jersey, United States
› Author Affiliations
Funding None.

Abstract

While primarily a hematologic disease, sickle cell anemia is notorious for its multisystemic manifestations, particularly in episodes of vaso-occlusive crisis. Multifocal acute calvarial infarction with associated epidural hemorrhage has rarely been reported in sickle cell vaso-occlusive crisis. In this article, we reported a unique case of a 15-year-old male presenting with sickle cell vaso-occlusive crisis and neuroimaging findings of multifocal calvarial bone infarction and epidural hemorrhage. Radiologists and clinicians should be cognizant of this rare complication of sickle cell anemia to ensure appropriate diagnosis and timely treatment.



Publication History

Received: 02 June 2021

Accepted: 09 July 2021

Article published online:
11 August 2021

© 2021. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 
  • References

  • 1 Lonergan GJ, Cline DB, Abbondanzo SL. Sickle cell anemia. Radiographics 2001; 21 (04) 971-994
  • 2 Ejindu VC, Hine AL, Mashayekhi M, Shorvon PJ, Misra RR. Musculoskeletal manifestations of sickle cell disease. Radiographics 2007; 27 (04) 1005-1021
  • 3 N'dri Oka D, Tokpa A, Bah A, Derou L. Spontaneous intracranial extradural hematoma in sickle cell disease. J Neurol Surg Rep 2015; 76 (01) e97-e99
  • 4 Arends S, Coebergh JA, Kerkhoffs JL, van Gils A, Koppen H. Severe unilateral headache caused by skull bone infarction with epidural haematoma in a patient with sickle cell disease. Cephalalgia 2011; 31 (12) 1325-1328
  • 5 Babatola BO, Salman YA, Abiola AM, Okezie KO, Oladele AS. Spontaneous epidural haematoma in sickle cell anaemia: case report and literature review. J Surg Tech Case Rep 2012; 4 (02) 135-137
  • 6 Komarla R, Soares BP, Chern JJ, Milla SS. Spontaneous epidural hematoma secondary to bone infarction in sickle cell anemia: case report. J Neurosurg Pediatr 2018; 22 (01) 18-21
  • 7 Iversen PO, Jacob M, Makame J. et al. A massive extradural hematoma in sickle cell disease and the importance of rapid neuroimaging. Case Rep Hematol 2019; 2019: 1742472
  • 8 Saul D, Pollock AN. Skull bone/calvarial infarction and spontaneous epidural hematoma as cause of severe headache in the emergency department. Pediatr Emerg Care 2017; 33 (12) 809-810
  • 9 Hettige S, Sofela A, Bassi S, Chandler C. A review of spontaneous intracranial extradural hematoma in sickle-cell disease. Acta Neurochir (Wien) 2015; 157 (11) 2025-2029 , discussion 2029
  • 10 Resar LM, Oliva MM, Casella JF. Skull infarction and epidural hematomas in a patient with sickle cell anemia. J Pediatr Hematol Oncol 1996; 18 (04) 413-415
  • 11 Novelli EM, Gladwin MT. Crises in sickle cell disease. Chest 2016; 149 (04) 1082-1093
  • 12 Barakat E, Guischer N, Houssiau F, Lecouvet FE. The “birth of death”: MRI step-by-step reveals the early appearance of a bone marrow infarct. Acta Radiol Open 2019; 8 (03) 2058460119834691