Journal of Pediatric Neurology 2022; 20(04): 283-286
DOI: 10.1055/s-0041-1736555
Case Report

A Pediatric Case of Benign Episodic Unilateral Mydriasis with Clinical Characteristics Resembling Tadpole Pupil

1   Department of Pediatrics and Adolescent Medicine, Aalborg University Hospital, Denmark
,
Pernille Kure Vandborg
2   Department of Pediatrics and Adolescent Medicine, Regional Hospital, Denmark
,
Jonas Kjeldbjerg Hansen
3   Department of Pediatrics and Adolescent Medicine, Aalborg University Hospital, Denmark
› Author Affiliations

Abstract

Benign episodic unilateral mydriasis is an episodic disturbance with dilatation of the entire pupil, often lasting for hours. It occurs most frequently in women aged between 20 and 50 years and is closely associated with migraines. Only a few pediatric cases have been reported. The demographics of benign unilateral mydriasis correspond to another episodic disturbance of the pupil, the tadpole pupil. Also, the clinical similarities between the two conditions are numerous. However, tadpole pupil is an irregular distortion of the pupil lasting from seconds to minutes and occurring in clusters. We present a 16-year-old girl with benign unilateral mydriasis and migraine. Her episodes of mydriasis lasted from seconds to minutes, occurred in clusters, and were thus like episodes of tadpole pupil. Benign unilateral mydriasis presenting this way has not been reported previously. This observation links the phenotypes of benign unilateral mydriasis and tadpole pupil closer together. The given case provides new knowledge as it (i) expands the clinical spectrum of benign episodic unilateral mydriasis, (ii) links the phenotypes of benign unilateral mydriasis and tadpole pupil together, and (iii) in comparison with knowledge about autonomic failure in migraine patients may add to hypotheses on pathophysiology in both pupillary disorders.



Publication History

Received: 23 June 2021

Accepted: 16 September 2021

Article published online:
25 October 2021

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