Video Comment on Rath et al.

Timo Rath et al. In vivo real-time assessment of colorectal polyp histology using an optical biopsy forceps system based on laser-induced fluorescence spectroscopy

This feasibility study examines a novel laser-induced fluorescence spectroscopy system, integrated into a biopsy forceps, for real-time automated prediction of the histology of diminutive polyps. The study, including 137 polyps (115 of them hyperplastic), showed good test characteristics with an accuracy of 84.7% and a negative predictive value for distal polyps of 100% (68 polyps in 19 patients).