Endoscopic submucosal dissection of the pharyngeal region using anchored hemoclip with surgical thread: A novel method

Background and study aims: Endoscopic submucosal dissection (ESD) of the pharyngeal region has not been well accepted, although ESD of the gastrointestinal tract is a standard procedure for treating early cancers. However, early detection and treatment of pharyngeal cancers is highly beneficial because surgical resection can be highly invasive and cause serious cosmetic deformities, swallowing disorders, dysgeusia, and speech defects. On the other hand, application of an anchored clip with surgical thread during ESD of the gastrointestinal tract has been reported to be beneficial. This pilot case series reveals the usefulness and clinical feasibility of applying a clip with thread in ESD of the pharyngeal region.

• References

• 1 Ota M, Nakamura T, Hayashi K et al. Usefulness of clip traction in the early phase of esophageal endoscopic submucosal dissection. Dig Endosc 2012; 24: 315-318
• 2 Yoshida M, Takizawa K, Ono H et al. Efficacy of endoscopic submucosal dissection with dental floss clip traction for gastric epithelial neoplasia: a pilot study (with video). Surg Endosc 2015;
• 3 Muto M, Minashi K, Yano T et al. Early detection of superficial squamous cell carcinoma in the head and neck region and esophagus by narrow band imaging: a multicenter randomized controlled trial. J Clin Oncol 2010; 28: 1566-1572
• 4 Shimizu Y, Yamamoto J, Kato M et al. Endoscopic submucosal dissection for treatment of early stage hypopharyngeal carcinoma. Gastrointest Endosc 2006; 64: 255-259 ; discussion 260-262
• 5 Kuwabara T, Hiyama T, Oka S et al. Clinical features of pharyngeal intraepithelial neoplasias and outcomes of treatment by endoscopic submucosal dissection. Gastrointest Endosc 2012; 76: 1095-1103
• 6 Tateya I, Muto M, Morita S et al. Endoscopic laryngo-pharyngeal surgery for superficial laryngo-pharyngeal cancer. Surg Endosc 2016; 30: 323-329
• 7 Lizuka T, Kikuchi D, Hoteya S et al. A new technique for pharyngeal endoscopic submucosal dissection: peroral countertraction (with video). Gastrointest Endosc 2012; 76: 1034-1038