Radiologie up2date 2016; 16(03): 251-266
DOI: 10.1055/s-0042-112447
Urogenitale Radiologie
© Georg Thieme Verlag KG Stuttgart · New York

Bildgebende Diagnostik gynäkologischer Notfälle

Imaging of gynecologic emergencies
M. W. Wagner
,
T. A. G. M. Huisman
,
R. A. Kubik
Further Information

Publication History

Publication Date:
14 September 2016 (online)

Zusammenfassung

Das akute Abdomen ist ein häufiges Krankheitsbild in der Notfalldiagnostik. Pathologische Veränderungen der weiblichen Genitalorgane spielen dabei eine wichtige Rolle. Gynäkologische Notfälle gefährden die Fertilität und sind potenziell lebensbedrohlich. Bei der Diagnostik sind viele Differenzialdiagnosen je nach Alter der Patientin und einer eventuellen Schwangerschaft zu beachten. Insbesondere akute gastrointestinale Beschwerden lassen sich in der klinischen Untersuchung oft nicht von gynäkologischen Notfällen unterscheiden. Die Bildgebung leistet hier einen wesentlichen Beitrag zur Einengung der Differenzialdiagnose, zur Therapieentscheidung und zum Therapiemonitoring. Im vorliegenden Übersichtsartikel soll der zentrale Stellenwert der Bildgebung im Rahmen häufiger gynäkologischer Notfälle erörtert werden.

Abstract

Acute abdominal pain related to the female genital organs is frequently encountered in the emergency department. Gynecological emergencies are diseases of the female reproductive system that are potentially life-threatening and peril the sexual function and fertility. In the diagnostic work-up of acute abdominal pain, a wide variety of differential diagnoses needs to be considered depending on the age of the patient and a concomitant pregnancy. There is significant clinical overlap with gastrointestinal emergencies. Therefore, imaging plays a key role in diagnosing the cause of the pain and the planning of the therapy. The aim of this review is to illustrate the significant role of imaging in frequently encountered gynaecologic emergencies.

Kernaussagen
  • Wenn die CT bei bei Kindern, Schwangeren oder Frauen im gebärfähigen Alter zum Einsatz kommt, sollte die Strahlendosis besonders beachtet werden. Es gilt das ALARA-Prinzip, d. h. die Dosis sollte „as low as reasonably achievable“ sein.

  • Die MRT dient zur Abklärung subakuter Krankheitsbilder und unklarer sonografischer Befunde. Bei eindeutiger Indikation und positivem Nutzen-Risiko-Verhältnis kann die MRT auch bei Schwangeren durchgeführt werden.

  • Der Hämatometrokolpos (distendierter, blutgefüllter Uterus und Vagina) ist in zwei Drittel aller Fälle durch die Hymenalatresie verursacht. Nach der initialen Abklärung mittels Ultraschall sollte eine assoziierte Nierenfehlbildung und eine Hydronephrose ausgeschlossen werden.

  • Die EUG ist der häufigste Notfall in der frühen Schwangerschaft und manifestiert sich i. d. R. in der Tuba uterina. Risikofaktoren sind u. a. „pelvic inflammatory disease“, Endometriose und Voroperationen. Ultraschallzeichen sind ein „blob-sign“ und ein „tubal ring-sign“. Die MRT dient lediglich zur Abklärung unklarer Fälle.

  • Leiomyome sind die häufigsten gynäkologischen Neoplasien. Die rote Degeneration des Leiomyoms ist eine wichtige Differenzialdiagnose des akuten Abdomens während der Schwangerschaft. Die Torsion eines Leiomyoms kann ebenfalls eine Ursache für ein akutes Abdomen sein.

 
  • Literatur

  • 1 Roche O, Chavan N, Aquilina J et al. Radiological appearances of gynaecological emergencies. Insights Imaging 2012; 3: 265-275
  • 2 Tirada N, Dreizin D, Khati NJ et al. Imaging Pregnant and Lactating Patients. Radiographics 2015; 35: 1751-1765
  • 3 Oto A, Ernst RD, Ghulmiyyah LM et al. MR imaging in the triage of pregnant patients with acute abdominal and pelvic pain. Abdom Imaging 2009; 34: 243-250
  • 4 Atri M, Leduc C, Gillett P et al. Role of endovaginal sonography in the diagnosis and management of ectopic pregnancy. Radiographics 1996; 16: 755-774
  • 5 Masselli G, Derchi L, McHugo J et al. Acute abdominal and pelvic pain in pregnancy: ESUR recommendations. Eur Radiol 2013; 23: 3485-3500
  • 6 Molins IG, Font JM, Alvaro JC et al. Contrast-enhanced ultrasound in diagnosis and characterization of focal hepatic lesions. World J Radiol 2010; 2: 455-462
  • 7 Nolsoe CP, Lorentzen T. International guidelines for contrast-enhanced ultrasonography: ultrasound imaging in the new millennium. Ultrasonography 2016; 35: 89-103
  • 8 Frohlich JM, Kubik-Huch RA. Radiographic, MR or ultrasound contrast media in pregnant or breast-feeding women: what are the key issues?. Rofo 2013; 185: 13-25
  • 9 Kubik-Huch RA, Gottstein-Aalame NM, Frenzel T et al. Gadopentetate dimeglumine excretion into human breast milk during lactation. Radiology 2000; 216: 555-558
  • 10 Posner JC, Spandorfer PR. Early detection of imperforate hymen prevents morbidity from delays in diagnosis. Pediatrics 2005; 115: 1008-1012
  • 11 Basaran M, Usal D, Aydemir C. Hymen sparing surgery for imperforate hymen: case reports and review of literature. J Pediatr Adolesc Gynecol 2009; 22: e61-64
  • 12 Fischer JW, Kwan CW. Emergency point-of-care ultrasound diagnosis of hematocolpometra and imperforate hymen in the pediatric emergency department. Pediatr Emerg Care 2014; 30: 128-130
  • 13 Dane C, Dane B, Erginbas M et al. Imperforate hymen-a rare cause of abdominal pain: two cases and review of the literature. J Pediatr Adolesc Gynecol 2007; 20: 245-247
  • 14 Drakonaki EE, Tritou I, Pitsoulis G et al. Hematocolpometra due to an imperforate hymen presenting with back pain: sonographic diagnosis. J Ultrasound Med 2010; 29: 321-322
  • 15 Poll LW, Flake P. Images in clinical medicine. Imperforate hymen with hematocolpometra. N Engl J Med 2011; 365: 157
  • 16 Krafft C, Hartin Jr CW, Ozgediz DE. Magnetic resonance as an aid in the diagnosis of a transverse vaginal septum. J Pediatr Surg 2012; 47: 422-425
  • 17 Beranger-Gibert S, Sakly H, Ballester M et al. Diagnostic Value of MR Imaging in the Diagnosis of Adnexal Torsion. Radiology 2016; 279: 461-470
  • 18 Damigos E, Johns J, Ross J. An update on the diagnosis and management of ovarian torsion. The Obstetrician & Gynaecologist 2012; 14: 229-236
  • 19 Hibbard LT. Adnexal torsion. Am J Obstet Gynecol 1985; 152: 456-461
  • 20 Duigenan S, Oliva E, Lee SI. Ovarian torsion: diagnostic features on CT and MRI with pathologic correlation. AJR Am J Roentgenol 2012; 198: W122-131
  • 21 Chang HC, Bhatt S, Dogra VS. Pearls and pitfalls in diagnosis of ovarian torsion. Radiographics 2008; 28: 1355-1368
  • 22 Pena JE, Ufberg D, Cooney N et al. Usefulness of Doppler sonography in the diagnosis of ovarian torsion. Fertil Steril 2000; 73: 1047-1050
  • 23 Chiou SY, Lev-Toaff AS, Masuda E et al. Adnexal torsion: new clinical and imaging observations by sonography, computed tomography, and magnetic resonance imaging. J Ultrasound Med 2007; 26: 1289-1301
  • 24 Wilkinson C, Sanderson A. Adnexal torsion – a multimodality imaging review. Clin Radiol 2012; 67: 476-483
  • 25 Lee EJ, Kwon HC, Joo HJ et al. Diagnosis of ovarian torsion with color Doppler sonography: depiction of twisted vascular pedicle. J Ultrasound Med 1998; 17: 83-89
  • 26 Albayram F, Hamper UM. Ovarian and adnexal torsion: spectrum of sonographic findings with pathologic correlation. J Ultrasound Med 2001; 20: 1083-1089
  • 27 Lourenco AP, Swenson D, Tubbs RJ et al. Ovarian and tubal torsion: imaging findings on US, CT, and MRI. Emerg Radiol 2014; 21: 179-187
  • 28 Rha SE, Byun JY, Jung SE et al. CT and MR imaging features of adnexal torsion. Radiographics 2002; 22: 283-294
  • 29 Hiller N, Appelbaum L, Simanovsky N et al. CT features of adnexal torsion. AJR Am J Roentgenol 2007; 189: 124-129
  • 30 Rajkotia K, Veeramani M, Macura KJ. Magnetic resonance imaging of adnexal masses. Top Magn Reson Imaging 2006; 17: 379-397
  • 31 Moribata Y, Kido A, Yamaoka T et al. MR imaging findings of ovarian torsion correlate with pathological hemorrhagic infarction. Journal of Obstetrics and Gynaecology Research 2015; 41: 1433-1439
  • 32 Hiller N, Sella T, Lev-Sagi A et al. Computed tomographic features of tuboovarian abscess. J Reprod Med 2005; 50: 203-208
  • 33 Jeong WK, Kim Y, Song SY. Tubo-ovarian abscess: CT and pathological correlation. Clin Imaging 2007; 31: 414-418
  • 34 Lee DC, Swaminathan AK. Sensitivity of ultrasound for the diagnosis of tubo-ovarian abscess: a case report and literature review. J Emerg Med 2011; 40: 170-175
  • 35 Wilbur AC, Aizenstein RI, Napp TE. CT findings in tuboovarian abscess. AJR Am J Roentgenol 1992; 158: 575-579
  • 36 Ellis JH, Francis IR, Rhodes M et al. CT findings in tuboovarian abscess. J Comput Assist Tomogr 1991; 15: 589-592
  • 37 Eshed I, Halshtok O, Erlich Z et al. Differentiation between right tubo-ovarian abscess and appendicitis using CT – a diagnostic challenge. Clin Radiol 2011; 66: 1030-1035
  • 38 Noone TC, Semelka RC, Worawattanakul S et al. Intraperitoneal abscesses: diagnostic accuracy of and appearances at MR imaging. Radiology 1998; 208: 525-528
  • 39 Dohke M, Watanabe Y, Okumura A et al. Comprehensive MR imaging of acute gynecologic diseases. Radiographics 2000; 20: 1551-1566
  • 40 Kim SH, Kim SH, Yang DM et al. Unusual causes of tubo-ovarian abscess: CT and MR imaging findings. Radiographics 2004; 24: 1575-1589
  • 41 Bakir B, Bakan S, Tunaci M et al. Diffusion-weighted imaging of solid or predominantly solid gynaecological adnexial masses: is it useful in the differential diagnosis?. Br J Radiol 2011; 84: 600-611
  • 42 Fujii S, Kakite S, Nishihara K et al. Diagnostic accuracy of diffusion-weighted imaging in differentiating benign from malignant ovarian lesions. J Magn Reson Imaging 2008; 28: 1149-1156
  • 43 Rezvani M, Shaaban AM, Kennedy AM. The role of multimodality imaging after cesarean delivery. Ultrasound Q 2015; 31: 5-18
  • 44 Brown CE, Stettler RW, Twickler D et al. Puerperal septic pelvic thrombophlebitis: incidence and response to heparin therapy. Am J Obstet Gynecol 1999; 181: 143-148
  • 45 Josey WE, Staggers Jr SR. Heparin therapy in septic pelvic thrombophlebitis: a study of 46 cases. Am J Obstet Gynecol 1974; 120: 228-233
  • 46 Garcia J, Aboujaoude R, Apuzzio J et al. Septic pelvic thrombophlebitis: diagnosis and management. Infect Dis Obstet Gynecol 2006; 2006: 1-4
  • 47 Kominiarek MA, Hibbard JU. Postpartum ovarian vein thrombosis: an update. Obstet Gynecol Surv 2006; 61: 337-342
  • 48 De Cuyper K, Eyselbergs M, Bernard P et al. Added value of diffusion weighted MR imaging in the diagnosis of postpartum ovarian vein thrombosis. Jbr-btr 2014; 97: 242-244
  • 49 Kataoka ML, Togashi K, Kobayashi H et al. Evaluation of ectopic pregnancy by magnetic resonance imaging. Hum Reprod 1999; 14: 2644-2650
  • 50 Della-Giustina D, Denny M. Ectopic pregnancy. Emerg Med Clin North Am 2003; 21: 565-584
  • 51 Tamai K, Koyama T, Togashi K. MR features of ectopic pregnancy. Eur Radiol 2007; 17: 3236-3246
  • 52 Refaat B, Dalton E, Ledger WL. Ectopic pregnancy secondary to in vitro fertilisation-embryo transfer: pathogenic mechanisms and management strategies. Reprod Biol Endocrinol 2015; 13: 30
  • 53 Baron KT, Babagbemi KT, Arleo EK et al. Emergent complications of assisted reproduction: expecting the unexpected. Radiographics 2013; 33: 229-244
  • 54 Braffman BH, Coleman BG, Ramchandani P et al. Emergency department screening for ectopic pregnancy: a prospective US study. Radiology 1994; 190: 797-802
  • 55 Condous G, Okaro E, Khalid A et al. The accuracy of transvaginal ultrasonography for the diagnosis of ectopic pregnancy prior to surgery. Hum Reprod 2005; 20: 1404-1409
  • 56 Shalev E, Yarom I, Bustan M et al. Transvaginal sonography as the ultimate diagnostic tool for the management of ectopic pregnancy: experience with 840 cases. Fertil Steril 1998; 69: 62-65
  • 57 Brown DL, Doubilet PM. Transvaginal sonography for diagnosing ectopic pregnancy: positivity criteria and performance characteristics. J Ultrasound Med 1994; 13: 259-266
  • 58 Sadek AL, Schiotz HA. Transvaginal sonography in the management of ectopic pregnancy. Acta Obstet Gynecol Scand 1995; 74: 293-296
  • 59 Yoshigi J, Yashiro N, Kinoshita T et al. Diagnosis of ectopic pregnancy with MRI: efficacy of T2*-weighted imaging. Magn Reson Med Sci 2006; 5: 25-32
  • 60 Murase E, Siegelman ES, Outwater EK et al. Uterine leiomyomas: histopathologic features, MR imaging findings, differential diagnosis, and treatment. Radiographics 1999; 19: 1179-1197
  • 61 McLucas B. Diagnosis, imaging and anatomical classification of uterine fibroids. Best Pract Res Clin Obstet Gynaecol 2008; 22: 627-642
  • 62 Furey EA, Bailey AA, Pedrosa I. Magnetic resonance imaging of acute abdominal and pelvic pain in pregnancy. Top Magn Reson Imaging 2014; 23: 225-242
  • 63 Ueda H, Togashi K, Konishi I et al. Unusual appearances of uterine leiomyomas: MR imaging findings and their histopathologic backgrounds. Radiographics 1999; 19: 131-145
  • 64 Potter AW, Chandrasekhar CA. US and CT evaluation of acute pelvic pain of gynecologic origin in nonpregnant premenopausal patients. Radiographics 2008; 28: 1645-1659
  • 65 Roy C, Bierry G, El Ghali S et al. Acute torsion of uterine leiomyoma: CT features. Abdom Imaging 2005; 30: 120-123
  • 66 Katz DS, Khalid M, Coronel EE et al. Computed tomography imaging of the acute pelvis in females. Can Assoc Radiol J 2013; 64: 108-118
  • 67 Kim JC, Kim SS, Park JY. “Bridging vascular sign” in the MR diagnosis of exophytic uterine leiomyoma. J Comput Assist Tomogr 2000; 24: 57-60
  • 68 Nishino M, Hayakawa K, Iwasaku K et al. Magnetic resonance imaging findings in gynecologic emergencies. J Comput Assist Tomogr 2003; 27: 564-570
  • 69 Grand DJ, Mayo-Smith WW, Woodfield CA. Practical Body MRI: Protocols, Applications and Image Interpretation. Cambridge: Cambridge University Press; 2012
  • 70 Walsh CA, Reardon W, Foley ME. Unexplained prelabor uterine rupture in a term primigravida. Obstet Gynecol 2007; 109: 455
  • 71 Pepin M, Schwarze U, Superti-Furga A et al. Clinical and genetic features of Ehlers-Danlos syndrome type IV, the vascular type. N Engl J Med 2000; 342: 673-680
  • 72 Khabbaz AY, Usta IM, El-Hajj MI et al. Rupture of an unscarred uterus with misoprostol induction: case report and review of the literature. J Matern Fetal Med 2001; 10: 141-145
  • 73 Moshiri M, Osman S, Bhargava P et al. Imaging evaluation of maternal complications associated with repeat cesarean deliveries. Radiol Clin North Am 2014; 52: 1117-1135
  • 74 Rodgers SK, Kirby CL, Smith RJ et al. Imaging after cesarean delivery: acute and chronic complications. Radiographics 2012; 32: 1693-1712
  • 75 Emans SJ et al. Pediatric and Adolescent Gynecology. Baltimore, Md: Lippincott Williams & Wilkins; 2005: 369
  • 76 Hueppchen N, Ling FW. Ectopic pregnancy and abortion. In: Beckmann CR, Ling FW, Smith RP, et al., (eds). Obstetrics and gynecology. 6th. ed. Baltimore, Md: Lippincott Williams & Wilkins; 2010: 142-143
  • 77 European Society of urogenital radiology. 9.0 Contrast Media Guidelines. Letztes Update: 20. 4. 2016. Im Internet: http://www.esur.org/esur-guidelines ; Stand: 30. 7. 2016