CC BY-NC-ND 4.0 · Journal of Gastrointestinal and Abdominal Radiology
DOI: 10.1055/s-0042-1742433
Case Report

Clinical and Radiological Features of Cronkhite–Canada Syndrome: A Case Report

Lokesh Lokesh
1   Department of Radiodiagnosis and Interventional Radiology, All India Institute of Medical Sciences, New Delhi, India
,
Vikas Jindal
2   Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi
,
Prasenjit Das
3   Department of Pathology, All India Institute of Medical Sciences, New Delhi
,
Rajni Yadav
3   Department of Pathology, All India Institute of Medical Sciences, New Delhi
,
Govind K. Makharia
2   Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi
,
Kumble Seetharama Madhusudhan
1   Department of Radiodiagnosis and Interventional Radiology, All India Institute of Medical Sciences, New Delhi, India
› Author Affiliations

Abstract

Cronkhite–Canada syndrome is a rare non-hereditary disease characterized by gastrointestinal hamartomatous polyposis and protein-losing enteropathy. The presenting symptoms are onychodystrophy, skin pigmentation, alopecia, weight loss, and diarrhea. Diagnosis is suggested by a combination of clinical, imaging, and endoscopy findings, and histology is necessary for confirmation. Here we describe a case of a 54-year-old man presenting with watery diarrhea, colicky abdominal pain, nasal obstruction, and weight loss for 6 months. Endoscopy showed multiple polyps in the stomach, duodenum, and colon. These were seen on computed tomography (CT) enterography along with polyps in the small bowel. A final diagnosis was made after the biopsy.



Publication History

Article published online:
01 February 2022

© 2022. Indian Society of Gastrointestinal and Abdominal Radiology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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