Abstract
Guillain–Barré Syndrome is an acute inflammatory demyelinating polyradiculoneuropathy
that can present at any age. The presentation of Guillain–Barré syndrome may be variable
as the classic symptoms of areflexia and flaccid paralysis may or may not be present.
Here we reported a case of a 15-year-old male patient who presented with complaints
of weakness in bilateral lower limbs with inability to sit along with slurred speech
and drooling of saliva with positive meningeal signs like neck stiffness and Kernig's
sign. His symptoms improved with immunoglobulin therapy. Five days later, the child
again had pain and increased weakness with increased work of breathing for which repeat
dose and course of immunoglobulins were given. As patients with signs of meningeal
irritation may suggest other diseases such as meningitis, it is important to consider
atypical cases of Guillain–Barré syndrome along with treatment-related fluctuations
as observed in our patient.
Keywords
meningeal signs - treatment-related fluctuations - polyradiculoneuropathy