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DOI: 10.1055/s-0042-1751416
Bioinspired Total Syntheses of Gymnothelignans
Autor*innen
We acknowledge the financial support from the National Natural Science Foundation of China (NSFC) (22171115, 21901093, 22231003, 21732001, 21871118, 22071090), Ministry of Education (MOE) (IRT_15R28), State Key Laboratory of Applied Organic Chemistry (SKLAOC), Lanzhou University (LZU) for the Fundamental Research Funds for the Central Universities (lzujbky-2022-58), and the Science and Technology Department of Gansu Province (22JR5RA397).
Abstract
Since 2012, Xu and Zhou have reported the isolation of a series of gymnotheligans, a large group of novel tetrahydrofuran-containing lignan natural products. In the past decade, considerable achievements in the total syntheses of these lignans have been achieved based on a plausible biogenetic pathway proposed by our group in 2014. In this account, we summarize these remarkable synthetic works of the past ten years.
1 Introduction
2 Biogenetic Pathways to Gymnothelignans
3 Total Syntheses of Eupodienones
4 Total Syntheses of Eupomatilones
5 Total Synthesis of Dibenzocyclooctenes
6 Conclusions
Key words
total synthesis - biogenetic pathway - gymnothelignans - eupodienone - eupomatilone - dibenzocyclooctenePublikationsverlauf
Eingereicht: 25. Dezember 2022
Angenommen nach Revision: 18. Januar 2023
Artikel online veröffentlicht:
09. Februar 2023
© 2023. Thieme. All rights reserved
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