CC BY-NC-ND 4.0 · Avicenna J Med 2022; 12(04): 182-185
DOI: 10.1055/s-0042-1756675
Case Report

Aldosterone-Secreting Large Oncocytic Neoplasm of the Adrenal Gland with Borderline Potential

Maher Alshaheen
1   Department of Internal Medicine, Bahrain Specialist Hospital, Manama, Kingdom of Bahrain
Krishanu Das
2   Department of Urology and Andrology, Bahrain Specialist Hospital. Manama, Kingdom of Bahrain
Mary Jean
3   Department of Pathology, Bahrain Specialist Hospital, Manama, Kingdom of Bahrain
4   Department for Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany
› Author Affiliations
Funding None.


Adrenal oncocytomas are rare tumors that are mostly benign and non-functional although they may be hormonally active and can exhibit a borderline or malignant potential. We present a case of a 40-year-old female patient with known hypertension who presented with abdominal discomfort. Radiologic investigations showed a large mass on the left adrenal gland. In the hormonal study, an aldosterone-secreting tumor was identified. After laparoscopic resection, the histological assessment of the 12-cm mass showed an oncocytic neoplasm with borderline characteristics. The laboratory results returned to normal and the hypertensive disease improved. The patient was doing well after 14 months of follow-up. This is the seventh documented case of aldosterone-secreting oncocytoma, the first borderline tumor of this type, and the largest reported tumor so far.

Patient Consent

Written informed consent was obtained from the patient and is available on request.

Authors' Contributions

K.D. operated on the patient and wrote the first draft. M.A. was involved in the diagnostic work-up and follow-up, collected the clinical data, and edited the manuscript. M.J. examined the specimen and contributed to the pathologic details of the work. M.F.S. researched the documented cases, organized the figures and tables, and edited the discussion. All authors reviewed and approved the final manuscript before submission.

Publication History

Article published online:
15 September 2022

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