CC BY-NC-ND 4.0 · Endosc Int Open 2017; 05(11): E1069-E1073
DOI: 10.1055/s-0043-118004
Case report
Eigentümer und Copyright ©Georg Thieme Verlag KG 2017

Magnifying image-enhanced endoscopy for collagenous colitis

Masaaki Kobayashi
1   Department of Gastroenterology and Hepatology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Niigata, Japan
,
Takahiro Hoshi
1   Department of Gastroenterology and Hepatology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Niigata, Japan
,
Shin-ich Morita
1   Department of Gastroenterology and Hepatology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Niigata, Japan
,
Tsutomu Kanefuji
1   Department of Gastroenterology and Hepatology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Niigata, Japan
,
Takeshi Suda
1   Department of Gastroenterology and Hepatology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Niigata, Japan
,
Go Hasegawa
2   Department of Pathology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Niigata, Japan
,
Shuji Terai
3   Division of Gastroenterology and Hepatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
› Author Affiliations
Further Information

Publication History

submitted 04 March 2017

accepted after revision 14 June 2017

Publication Date:
27 October 2017 (online)

Abstract

Background and study aims We report a case series of 5 patients with collagenous colitis (CC) presenting with chronic watery diarrhea, who were subjected to magnifying, chromoendoscopy and narrow band imaging (NBI). Magnifying chromoendoscopy revealed whitish-clouded, honeycomb-like appearance at orifices of the crypts. NBI with high magnification revealed irregular caliber variation of the subepithelial capillary network. Presence of these features corresponded with histological characteristics of CC indicated by thickening of the subepithelial collagen layer. We concluded that magnifying image-enhanced endoscopy is a reliable tool to diagnose CC.

 
  • References

  • 1 Gledhill A, Cole FM. Significance of basement membrane thickening in the human colon. Gut 1984; 25: 1085-1088
  • 2 Kakar S, Pardi DS, Burgart LJ. Colonic ulcers accompanying collagenous colitis: implication of nonsteroidal anti-inflammatory drugs. Am J Gastroenterol 2003; 98: 1834-1837
  • 3 Umeno J, Matsumoto T, Nakamura S. et al. Linear mucosal defect may be characteristic of lansoprazole-associated collagenous colitis. Gastrointest Endosc 2008; 67: 1185-1191
  • 4 Bohr J, Tysk C, Eriksson S. et al. Collagenous colitis: a retrospective study of clinical presentation and treatment in 163 patients. Gut 1996; 39: 846-851
  • 5 Koulaouzidis A, Yung DE, Nemeth A. et al. Macroscopic findings in collagenous colitis: a multi-center, retrospective, observational cohort study. Ann Gastroenterol 2017; 30: 309-314
  • 6 Morita T, Yamamoto S, Takeuchi E. Narrow band imaging for diagnosis of collagenous colitis. Dig Endosc 2014; 26: 752-753
  • 7 Cimmino DG, Mella JM, Pereyra L. et al. A colorectal mosaic pattern might be an endoscopic feature of collagenous colitis. J Crohns Colitis 2010; 4: 139-143
  • 8 Koulaouzidis A, Saeed AA. Distinct colonoscopy findings of microscopic colitis: not so microscopic after all?. World J Gastroenterol 2011; 17: 4157-4165
  • 9 Suzuki G, Mellander MR, Suzuki A. et al. Usefulness of colonoscopic examination with indigo carmine in diagnosing microscopic colitis. Endoscopy 2011; 43: 1100-1104
  • 10 Yung DE, Koulaouzidis A, Fineron P. et al. Microscopic colitis: a misnomer for a clearly defined entity?. Endoscopy 2015; 47: 754-757
  • 11 Kiesslich R, Hoffman A, Goetz M. et al. In vivo diagnosis of collagenous colitis by confocal endomicroscopy. Gut 2006; 55: 591-592
  • 12 Zambelli A, Villanacci V, Buscarini E. et al. Collagenous colitis: a case series with confocal laser microscopy and histology correlation. Endoscopy 2008; 40: 606-608