Akutes Leberversagen als seltene Manifestation einer häufigen Erkrankung

Zusammenfassung

Eine 63-jährige Patientin wurde mit Verdacht auf akutes Leberversagen aufgenommen. Als Ursache konnte eine akute Hepatitis-C-Virus (HCV)-Infektion identifiziert werden. Im Verlauf kam es zu einer spontanen Ausheilung der Infektion mit Stabilisierung der Leberfunktion. Ein akutes Leberversagen auf dem Boden einer akuten HCV-Infektion ist sehr selten und wurde bisher kaum beschrieben. Dennoch muss die akute HCV-Infektion als seltene Differenzialdiagnose eines akuten Leberversagens beachtet werden.

Abstract

Here we report the case of a 63-year-old female patient who was admitted with acute liver failure. The etiology turned out to be an acute fulminant hepatitis caused by hepatitis C virus (HCV) infection of unknown origin. Fulminant hepatitis due to acute hepatitis C is very rare and hardly reported but a potential cause of acute liver failure due to massive hepatic necrosis, which may lead to encephalitis and multi-organ-failure. During follow-up spontaneous virological clearance was observed. The case illustrates that acute HCV infection, which is confirmed by the detection of HCV-RNA, has to be considered in the differential diagnosis of acute liver failure.

Schlüsselwörter

akutes Leberversagen - akute Hepatitis C - Hepatitis-C-Virus

Key words

acute liver failure - acute hepatitis C - hepatitis C virus

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