CC BY-NC-ND 4.0 · Semin Hear 2023; 44(01): 029-045
DOI: 10.1055/s-0043-1764200
Original Article

Use of Wideband Acoustic Immittance in Neonates and Infants

Hammam AlMakadma
1   Department of Otolaryngology and Communicative Disorders, School of Medicine, University of Louisville, Louisville, Kentucky
,
Sreedevi Aithal
2   Hearing Research Unit for Children, School of Health and Rehabilitative Sciences, The University of Queensland, Queensland, Australia
3   Department of Audiology, Townsville University Hospital, Townsville, Australia
,
Venkatesh Aithal
2   Hearing Research Unit for Children, School of Health and Rehabilitative Sciences, The University of Queensland, Queensland, Australia
3   Department of Audiology, Townsville University Hospital, Townsville, Australia
,
Joseph Kei
2   Hearing Research Unit for Children, School of Health and Rehabilitative Sciences, The University of Queensland, Queensland, Australia
› Author Affiliations

Abstract

With widespread agreement on the importance of early identification of hearing loss, universal newborn hearing screening (UNHS) has become the standard of care in several countries. Despite advancements in screening technology, UNHS and early hearing detection and intervention programs continue to be burdened by high referral rates of false-positive cases due to temporary obstruction of sound in the outer/middle ear at birth. A sensitive adjunct test of middle ear at the time of screening would aid in the interpretation of screening outcomes, minimize unnecessary rescreens, and prioritize referral to diagnostic assessment for infants with permanent congenital hearing loss. Determination of middle ear status is also an important aspect of diagnostic assessment in infants. Standard single-frequency tympanometry used to determine middle ear status in infants is neither efficient nor accurate in newborns and young infants. A growing body of research has demonstrated the utility of wideband acoustic immittance (WAI) testing in both screening and diagnostic settings. Wideband power absorbance (WBA), a WAI measure, has been shown to be more sensitive than tympanometry in the assessment of outer/middle ear function in newborns. Furthermore, age-graded norms also support successful application of WBA in young infants. Despite its merits, uptake of this technology is low among pediatric audiologists and hearing screening health workers. This report describes normative data, methods for assessment and interpretation of WBA, test–retest variations, and other factors pertinent to clinical use of WAI in newborns and infants. Clinical cases illustrate the use of WAI testing in newborn and infant hearing assessment.

* H.A. and S.A. have jointly contributed as first authors.




Publication History

Article published online:
01 March 2023

© 2023. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

Thieme Medical Publishers, Inc.
333 Seventh Avenue, 18th Floor, New York, NY 10001, USA

 
  • References

  • 1 World Health Organization. . Newborn and infant hearing screening: current issues and guiding principles for action. WHO Press. Accessed August 5, 2015 at: http://www.who.int/blindness/publications/Newborn_and_Infant_Hearing_Screening_Report.pdf
  • 2 Gaffney M, Eichwald J, Gaffney C, Alam S. Centers for Disease Control and Prevention (CDC). Early hearing detection and intervention among infants--hearing screening and follow-up survey, United States, 2005-2006 and 2009-2010. MMWR Suppl 2014; 63 (02) 20-26
  • 3 American Academy of Pediatrics, Joint Committee on Infant Hearing. Year 2007 position statement: principles and guidelines for early hearing detection and intervention programs. Pediatrics 2007; 120 (04) 898-921
  • 4 Center for Disease Control and Prevention. . Summary of 2016 National CDC EHDI Data. Accessed December 2, 2019 at: https://www.cdc.gov/ncbddd/hearingloss/2016-data/01-2016-HSFS-Data-Summary-h.pdf
  • 5 Yoshinaga-Itano C, Coulter D, Thomson V. The Colorado Newborn Hearing Screening Project: effects on speech and language development for children with hearing loss. J Perinatol 2000; 20 (8, Pt 2): S132-S137
  • 6 Yoshinaga-Itano C, Sedey AL, Coulter DK, Mehl AL. Language of early- and later-identified children with hearing loss. Pediatrics 1998; 102 (05) 1161-1171
  • 7 Chang KW, Vohr BR, Norton SJ, Lekas MD. External and middle ear status related to evoked otoacoustic emission in neonates. Arch Otolaryngol Head Neck Surg 1993; 119 (03) 276-282
  • 8 Doyle KJ, Rodgers P, Fujikawa S, Newman E. External and middle ear effects on infant hearing screening test results. Otolaryngol Head Neck Surg 2000; 122 (04) 477-481
  • 9 Stuart A, Yang EY, Green WB. Neonatal auditory brainstem response thresholds to air- and bone-conducted clicks: 0 to 96  hours postpartum. J Am Acad Audiol 1994; 5 (03) 163-172
  • 10 McLellan MS, Brown JR, Rondeau H, Shoughro E, Johnson RA, Hale AR. Embryonal connective tissue and exudate in ear: a histological study of ear sections of fetuses and infants. Am J Dis Child 1964; 108 (02) 164-170
  • 11 Cavanaugh Jr RM. Pneumatic otoscopy in healthy full-term infants. Pediatrics 1987; 79 (04) 520-523
  • 12 Prieve B, Dalzell L, Berg A. et al. The New York State universal newborn hearing screening demonstration project: outpatient outcome measures. Ear Hear 2000; 21 (02) 104-117
  • 13 Kennedy CR. Wessex Universal Neonatal Screening Trial Group. Controlled trial of universal neonatal screening for early identification of permanent childhood hearing impairment: coverage, positive predictive value, effect on mothers and incremental yield. Acta Paediatr Suppl 1999; 88 (432) 73-75
  • 14 Thompson DC, McPhillips H, Davis RL, Lieu TL, Homer CJ, Helfand M. Universal newborn hearing screening: summary of evidence. JAMA 2001; 286 (16) 2000-2010
  • 15 Aithal S, Aithal V, Kei J, Driscoll C. Conductive hearing loss and middle ear pathology in young infants referred through a newborn universal hearing screening program in Australia. J Am Acad Audiol 2012; 23 (09) 673-685
  • 16 Rhodes MC, Margolis RH, Hirsch JE, Napp AP. Hearing screening in the newborn intensive care nursery: comparison of methods. Otolaryngol Head Neck Surg 1999; 120 (06) 799-808
  • 17 Paradise JL. Pediatrician's view of middle ear effusions: more questions than answers. Ann Otol Rhinol Laryngol 1976; 85 (2, Suppl; 25, Pt 2): 20-24
  • 18 Balkany T, Zarnoch J. Impedance tympanometry in infants. Audiology and Hearing Education 1978; 17-19
  • 19 Kei J, Allison-Levick J, Dockray J. et al. High-frequency (1000  Hz) tympanometry in normal neonates. J Am Acad Audiol 2003; 14 (01) 20-28
  • 20 Swanepoel W, Werner S, Hugo R, Louw B, Owen R, Swanepoel A. High frequency immittance for neonates: a normative study. Acta Otolaryngol 2007; 127 (01) 49-56
  • 21 Baldwin M. Choice of probe tone and classification of trace patterns in tympanometry undertaken in early infancy. Int J Audiol 2006; 45 (07) 417-427
  • 22 Marchant CD, McMillan PM, Shurin PA. et al. Objective diagnosis of otitis media in early infancy by tympanometry and ipsilateral acoustic reflex thresholds. J Pediatr 1986; 109 (04) 590-595
  • 23 Vanhuyse VJ, Creten WL, Van Camp KJ. On the W-notching of tympanograms. Scand Audiol 1975; 4: 45-55
  • 24 Alaerts J, Luts H, Wouters J. Evaluation of middle ear function in young children: clinical guidelines for the use of 226- and 1,000-Hz tympanometry. Otol Neurotol 2007; 28 (06) 727-732
  • 25 Margolis RH, Bass-Ringdahl S, Hanks WD, Holte L, Zapala DA. Tympanometry in newborn infants–1  kHz norms. J Am Acad Audiol 2003; 14 (07) 383-392
  • 26 Kei J, Mazlan R, Hickson L, Gavranich J, Linning R. Measuring middle ear admittance in newborns using 1000  Hz tympanometry: a comparison of methodologies. J Am Acad Audiol 2007; 18 (09) 739-748
  • 27 Williams MJ, Purdy SC, Barber C. High frequency probe tone tympanometry in infants with middle ear effusion. Aust J Otolaryngol 1995; 2: 169-173
  • 28 Sanford CA, Keefe DH, Liu Y-W. et al. Sound-conduction effects on distortion-product otoacoustic emission screening outcomes in newborn infants: test performance of wideband acoustic transfer functions and 1-kHz tympanometry. Ear Hear 2009; 30 (06) 635-652
  • 29 Hunter LL, Feeney MP, Lapsley Miller JA, Jeng PS, Bohning S. Wideband reflectance in newborns: normative regions and relationship to hearing-screening results. Ear Hear 2010; 31 (05) 599-610
  • 30 Aithal S, Kei J, Driscoll C, Khan A, Swanston A. Wideband absorbance outcomes in newborns: a comparison with high-frequency tympanometry, automated brainstem response, and transient evoked and distortion product otoacoustic emissions. Ear Hear 2015; 36 (05) e237-e250
  • 31 Keefe DH, Gorga MP, Neely ST, Zhao F, Vohr BR. Ear-canal acoustic admittance and reflectance measurements in human neonates. II. Predictions of middle-ear in dysfunction and sensorineural hearing loss. J Acoust Soc Am 2003; 113 (01) 407-422
  • 32 Hunter LL, Tubaugh L, Jackson A, Propes S. Wideband middle ear power measurement in infants and children. J Am Acad Audiol 2008; 19 (04) 309-324
  • 33 Keefe DH, Bulen JC, Arehart KH, Burns EM. Ear-canal impedance and reflection coefficient in human infants and adults. J Acoust Soc Am 1993; 94 (05) 2617-2638
  • 34 Keefe DH, Folsom RC, Gorga MP, Vohr BR, Bulen JC, Norton SJ. Identification of neonatal hearing impairment: ear-canal measurements of acoustic admittance and reflectance in neonates. Ear Hear 2000; 21 (05) 443-461
  • 35 Keefe DH, Levi E. Maturation of the middle and external ears: acoustic power-based responses and reflectance tympanometry. Ear Hear 1996; 17 (05) 361-373
  • 36 Merchant GR, Horton NJ, Voss SE. Normative reflectance and transmittance measurements on healthy newborn and 1-month-old infants. Ear Hear 2010; 31 (06) 746-754
  • 37 Rosen B, AlMakadma H, Sanford C. . An absorbance peak template for assessment of newborn conductive pathways. Presented at: Abstract of 47th Annual Scientific and Technology Conference of the American Auditory Society; March (5–7) 2020; Scottsdale, AZ. Accessed February 5, 2023 at: https://aas.memberclicks.net/assets/19_Posters.pdf
  • 38 AlMakadma HA, Prieve BA. Refining measurements of power absorbance in newborns: probe fit and intrasubject variability. Ear Hear 2021; 42 (03) 531-546
  • 39 Meyer SE, Jardine CA, Deverson W. Developmental changes in tympanometry: a case study. Br J Audiol 1997; 31 (03) 189-195
  • 40 Johnson JL, White KR, Widen JE. et al. A multicenter evaluation of how many infants with permanent hearing loss pass a two-stage otoacoustic emissions/automated auditory brainstem response newborn hearing screening protocol. Pediatrics 2005; 116 (03) 663-672
  • 41 Ikui A, Sando I, Haginomori S, Sudo M. Postnatal development of the tympanic cavity: a computer-aided reconstruction and measurement study. Acta Otolaryngol 2000; 120 (03) 375-379
  • 42 Qi L, Liu H, Lutfy J, Funnell WR, Daniel SJ. A nonlinear finite-element model of the newborn ear canal. J Acoust Soc Am 2006; 120 (06) 3789-3798
  • 43 Ikui A, Sando I, Sudo M, Fujita S. Postnatal change in angle between the tympanic annulus and surrounding structures. Computer-aided three-dimensional reconstruction study. Ann Otol Rhinol Laryngol 1997; 106 (01) 33-36
  • 44 Ruah CB, Schachern PA, Zelterman D, Paparella MM, Yoon TH. Age-related morphologic changes in the human tympanic membrane. A light and electron microscopic study. Arch Otolaryngol Head Neck Surg 1991; 117 (06) 627-634
  • 45 Kei J, Sanford CA, Prieve BA, Hunter LL. Wideband acoustic immittance measures: developmental characteristics (0 to 12 months). Ear Hear 2013; 34 (Suppl (Suppl. 01) 17S-26S
  • 46 Aithal S, Kei J, Driscoll C. Wideband absorbance in young infants (0-6 months): a cross-sectional study. J Am Acad Audiol 2014; 25 (05) 471-481
  • 47 Sanford CA, Feeney MP. Effects of maturation on tympanometric wideband acoustic transfer functions in human infants. J Acoust Soc Am 2008; 124 (04) 2106-2122
  • 48 Hunter LL, Keefe DH, Feeney MP, Fitzpatrick DF, Lin L. Longitudinal development of wideband reflectance tympanometry in normal and at-risk infants. Hear Res 2016; 340: 3-14
  • 49 Shekelle P, Takata G, Chan LS. et al. Diagnosis, natural history, and late effects of otitis media with effusion. Evid Rep Technol Assess (Summ) 2002; 55 (55) 1-5
  • 50 Friel-Patti S, Finitzo T. Language learning in a prospective study of otitis media with effusion in the first two years of life. J Speech Hear Res 1990; 33 (01) 188-194
  • 51 Roberts J, Wallace IF. . Language and otitis media. In: Roberts J, Wallace IF, eds. Otitis Media in Young Children. Brookes; 1997:133–162
  • 52 Vander Werff KR, Prieve BA, Georgantas LM. Test-retest reliability of wideband reflectance measures in infants under screening and diagnostic test conditions. Ear Hear 2007; 28 (05) 669-681
  • 53 Prieve BA, Vander Werff KR, Preston JL, Georgantas L. Identification of conductive hearing loss in young infants using tympanometry and wideband reflectance. Ear Hear 2013; 34 (02) 168-178
  • 54 Werner LA, Levi EC, Keefe DH. Ear-canal wideband acoustic transfer functions of adults and two- to nine-month-old infants. Ear Hear 2010; 31 (05) 587-598
  • 55 Shahnaz N, Cai A, Qi L. Understanding the developmental course of the acoustic properties of the human outer and middle ear over the first 6 months of life by using a longitudinal analysis of power reflectance at ambient pressure. J Am Acad Audiol 2014; 25 (05) 495-511
  • 56 Mimosa Acoustics Inc. . (2014) HearID 5.1   +   MEPA3 Module User's Manual. Mimosa Acoustics, Inc. Champaign, IL 61820
  • 57 Voss SE, Herrmann BS, Horton NJ, Amadei EA, Kujawa SG. Reflectance measures from infant ears with normal hearing and transient conductive hearing loss. Ear Hear 2016; 37 (05) 560-571
  • 58 Keefe DH, Hunter LL, Feeney MP, Fitzpatrick DF. Procedures for ambient-pressure and tympanometric tests of aural acoustic reflectance and admittance in human infants and adults. J Acoust Soc Am 2015; 138 (06) 3625-3653
  • 59 Aithal V, Kei J, Driscoll C. et al. Normative sweep frequency impedance measures in healthy neonates. J Am Acad Audiol 2014; 25 (04) 343-354
  • 60 Shahnaz N, Bork K, Polka L, Longridge N, Bell D, Westerberg BD. Energy reflectance and tympanometry in normal and otosclerotic ears. Ear Hear 2009; 30 (02) 219-233
  • 61 Wali HA, Mazlan R, Kei J. Pressurized wideband absorbance findings in healthy neonates: a preliminary study. J Speech Lang Hear Res 2017; 60 (10) 2965-2973
  • 62 Voss SE, Stenfelt S, Neely ST, Rosowski JJ. Factors that introduce intrasubject variability into ear-canal absorbance measurements. Ear Hear 2013; 34 (7 0 1, Suppl 1): 60S-64S
  • 63 Aithal S, Kei J, Aithal V. et al. Normative study of wideband acoustic immittance measures in newborn infants. J Speech Lang Hear Res 2017; 60 (05) 1417-1426
  • 64 Keefe DH, Simmons JL. Energy transmittance predicts conductive hearing loss in older children and adults. J Acoust Soc Am 2003; 114 (6, Pt 1): 3217-3238
  • 65 Margolis RH, Saly GL, Keefe DH. Wideband reflectance tympanometry in normal adults. J Acoust Soc Am 1999; 106 (01) 265-280
  • 66 Beers AN, Shahnaz N, Westerberg BD, Kozak FK. Wideband reflectance in normal Caucasian and Chinese school-aged children and in children with otitis media with effusion. Ear Hear 2010; 31 (02) 221-233
  • 67 Ellison JC, Gorga M, Cohn E, Fitzpatrick D, Sanford CA, Keefe DH. Wideband acoustic transfer functions predict middle-ear effusion. Laryngoscope 2012; 122 (04) 887-894
  • 68 Keefe DH, Sanford CA, Ellison JC, Fitzpatrick DF, Gorga MP. Wideband aural acoustic absorbance predicts conductive hearing loss in children. Int J Audiol 2012; 51 (12) 880-891
  • 69 Holte L, Margolis RH, Cavanaugh Jr RM. Developmental changes in multifrequency tympanograms. Audiology 1991; 30 (01) 1-24
  • 70 Sanford CA, Hunter LL, Feeney MP, Nakajima HH. Wideband acoustic immittance: tympanometric measures. Ear Hear 2013; 34 (Suppl (Suppl. 01) 65S-71S
  • 71 Aithal S, Aithal V, Kei J. Effect of ear canal pressure and age on wideband absorbance in young infants. Int J Audiol 2017; 56 (05) 346-355
  • 72 Shahnaz N, Feeney MP, Schairer KS. Wideband acoustic immittance normative data: ethnicity, gender, aging, and instrumentation. Ear Hear 2013; 34 (Suppl (Suppl. 01) 27S-35S
  • 73 AlMakadma H. . Refining the Clinical Measurement Of Wideband Acoustic Immittance In Newborns. Ph.D. dissertation. Dissertation Syracuse University. 2017. Accessed February 7, 2023 at: https://surface.syr.edu/etd/795
  • 74 AlMakadma H, Prieve B. . Wideband acoustic immittance testing in newborns: effect of measurement system. Presented at: Abstract of 46th Annual Scientific and Technology Conference of the American Auditory Society; February 28 to March 2, 2019; Scottsdale, AZ. Accessed February 7, 2023 at: https://aas.memberclicks.net/assets/19_Posters.pdf
  • 75 Rosowski JJ, Wilber LA. . Acoustic Immittance, Absorbance, and Reflectance in the Human Ear Canal. Thieme Medical Publishers; 2015:11–28
  • 76 Joint Committee on Infant Hearing. Year 2019 position statement: principles and guidelines for early hearing detection and intervention programs. J Early Hear Detect Interv 2019; 4 (02) 1-44