RSS-Feed abonnieren
PDF herunterladen
DOI: 10.1055/s-0043-1774735
Clinical and Imaging Research in the Diagnosis of Anorectal Melanoma with Surgical Outcome: A Case Report and Literature Review
Authors
Abstract
Objective This study aims to report the case of a 69-year-old female patient with a diagnosis of anorectal melanoma (AM) established by immunohistochemistry.
Methods Clinical case report, a descriptive and qualitative study.
Results The patient had a nodular and ulcerative lesion in the anal region, the imaging exams revealed an expansive lesion that affected the rectum and the vaginal wall. The chosen course of treatment was initial surgical intervention, the surgery and postoperative course progressed without complications, and the anatomopathological examination confirmed the diagnosis of invasive malignant melanoma of the distal rectum of anorectal transition. The anatomopathological examination confirmed the diagnosis of invasive malignant melanoma located in the distal rectum of the anorectal transition. Immunohistochemistry analysis showed infiltrative melanoma with microsatellites, as well as peri and intratumoral lymphocytic infiltrate, angiolymphatic invasion, and perineural invasion. The surgical resection margins, ovaries, posterior vaginal wall, and parametrium showed no signs of neoplastic involvement. Following the surgery, the patient began immunotherapy, which she is still undergoing.
Conclusions The survival rate of AM can be improved through various diagnostic and therapeutic modalities. However, further exploration of this topic through clinical studies is necessary to enhance both diagnosis and treatment.
Santa Casa de Curitiba, Paraná, Brasil
Publikationsverlauf
Eingereicht: 04. November 2022
Angenommen: 21. Juni 2023
Artikel online veröffentlicht:
21. September 2023
© 2023. Sociedade Brasileira de Coloproctologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
Thieme Revinter Publicações Ltda.
Rua do Matoso 170, Rio de Janeiro, RJ, CEP 20270-135, Brazil
-
References
- 1 Jutten E, Kruijff S, Francken AB. et al. Surgical treatment of anorectal melanoma: a systematic review and meta-analysis. BJS Open 2021; 5 (06) zrab107
- 2 de Meira Júnior JD, Sobrado LF, Guzela VM, Nahas SC, Sobrado CW. Anorectal Mucosal Melanoma: A Case Report and Literature Review. Am J Case Rep 2021; 22: e933032
- 3 Apostu RC, Stefanescu E, Scurtu RR, Kacso G, Drasovean R. Difficulties in diagnosing anorectal melanoma: A case report and review of the literature. World J Clin Cases 2021; 9 (36) 11369-11381
- 4 Husa A, Höckerstedt K. Anorectal malignant melanoma. A report of fourteen cases. Acta Chir Scand 1974; 140 (01) 68-72
- 5 Abbas JS, Karakousis CP, Holyoke ED. Anorectal melanoma: clinical features, recurrence and patient survival. Int Surg 1980; 65 (05) 423-426
- 6 Droesch JT, Flum DR, Mann GN. Wide local excision or abdominoperineal resection as the initial treatment for anorectal melanoma?. Am J Surg 2005; 189 (04) 446-449
- 7 Latteri S, Teodoro M, Malaguarnera M, Mannino M, Currò G, La Greca G. Abdominal perineal resection or wilde local excision in primary anorectal malignant melanoma. Case report and review. Ann Med Surg (Lond) 2017; 19 (19) 74-77