Semin Reprod Med 2023; 41(01/02): 037-044
DOI: 10.1055/s-0043-1777720
Review Article

Considerations in the Treatment of Depression and Anxiety in Women with PCOS

1   Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, New York
,
Anuja Dokras
2   Department of Obstetrics and Gynecology, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania
› Author Affiliations
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Abstract

Women with polycystic ovary syndrome (PCOS) are known to be at a greater risk of depression and anxiety. What is less clear is whether existing treatments for PCOS are effective in managing this increased risk and what the optimal approach to treatment is. In this review, currently available interventions are explored including lifestyle modifications, oral contraceptives, insulin sensitizing agents, psychosocial interventions and psychiatric medications. While data are often conflicting, lifestyle interventions, and cognitive behavioral therapy (CBT) appear most promising in reducing depression and anxiety symptoms in this population. There is an urgent need for large prospective studies to fill gaps in the literature.



Publication History

Article published online:
19 December 2023

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