Endoscopy 2025; 57(S 02): S224
DOI: 10.1055/s-0045-1805551
Abstracts | ESGE Days 2025
Moderated poster
EUS guided tissue acquisition: Needles and techniques 04/04/2025, 10:00 – 11:00 Poster Dome 1 (P0)

Non-inferiority wet suction compared to dry suction endoscopic fine needle biopsy in pancreatic solid lesions

Authors

  • A Seicean

    1   University of Medicine and Pharmacy 'Iuliu Haţieganu' Cluj-Napoca, Strada Emil Isac, Cluj-Napoca, Romania

  • S Viziteu

    2   Regional Institute of Gastroenterology and Hepatology O. Fodor Cluj-Napoca, Romania, Cluj, Romania

  • C Hagiu

    3   Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania

  • O Mosteanu

    3   Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania

  • N V Rednic

    4   Regional Institute of Gastroenterology and Hepatology O. Fodor, Cluj-Napoca, Romania

  • I Dragomir

    3   Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania

  • E Seulean

    4   Regional Institute of Gastroenterology and Hepatology O. Fodor, Cluj-Napoca, Romania

  • C Brinzila

    4   Regional Institute of Gastroenterology and Hepatology O. Fodor, Cluj-Napoca, Romania

  • R I Orzan

    4   Regional Institute of Gastroenterology and Hepatology O. Fodor, Cluj-Napoca, Romania

  • P Cristina

    4   Regional Institute of Gastroenterology and Hepatology O. Fodor, Cluj-Napoca, Romania

  • I Rusu

    4   Regional Institute of Gastroenterology and Hepatology O. Fodor, Cluj-Napoca, Romania
Further Information
Also available at
 

Aims To compare the diagnostic accuracy of dry suction versus wet suction technique in solid pancreatic lesions using 22G Franseen needles during endoscopic ultrasound fine needle biopsy(EUS-FNB)

Methods This is single-center prospective, observational trial with two dependent groups, comparing dry suction and wet suction in solid pancreatic lesions. Patients with necrosis, prior surgery, or chemotherapy were excluded from the trial. The primary endpoint was diagnostic accuracy. Secondary outcomes included pathological assessment such as length of the core, total surface of tissue samples, number of fragments, blood contamination, cellularity and adequacy for immunohistochemistry.

Results There were 88 samples assessed histologically from 44 solid pancreatic lesions, mean size was 29mm. The most common lesion location was the head 72,7% and, only 27,2% in body-tail. Among them, 29 (65%) of them were adenocarcinomas, 8 (18%) were chronic pancreatitis, 4 (9%) were adenocarcinomas with squamous differentiation, 2 were neuroendocrine tumors (NETs) and 1 was pancreatic metastasis. The sensitivity and accuracy of EUS diagnostic for malignancy in dry suctions pass vs wet suction pass were 91% vs 91% and 93% vs 93%. There was no difference when using wet suction compared with dry suction for the maximum core length (3 mm vs 4 mm, p=0.814), the number of fragments (10 vs. 8.5, p=0.352), the total surface of tissue sampled (6.25mm2 vs. 6.5mm2; p=0.866), moderate or severe blood contamination (65% vs. 63%, p=0.648) or median cellularity (25±33.5 IQR vs. 25±37,5 IQR, p=0.850). Tissue samples were adequate for immunohistochemistry in 95% of cases in the wet suction group and 91% in the dry suction group, with no statistical difference between the two (p=0.676).

Conclusions No superiority was demonstrated for wet suction EUS-FNB against dry suction EUS-FNB for the diagnostic rate and sample adequacy in solid pancreatic masses.



Publication History

Article published online:
27 March 2025

© 2025. European Society of Gastrointestinal Endoscopy. All rights reserved.

Georg Thieme Verlag KG
Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany