Endoscopy 2025; 57(S 02): S238-S239
DOI: 10.1055/s-0045-1805582
Abstracts | ESGE Days 2025
Moderated poster
Endoscopic therapy in the upper GI tract: From Bariatrics to EUS anastomosis 04/04/2025, 14:00 – 15:00 Poster Dome 1 (P0)

Weight loss impact on quality of life after endoscopic sleeve gastroplasty in adolescent population

Authors

  • L Gualtieri

    1   Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy

  • M De Siena

    2   Digestive Endoscopy, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy, Rome, Italy

  • M V Matteo

    2   Digestive Endoscopy, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy, Rome, Italy

  • G Carlino

    2   Digestive Endoscopy, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy, Rome, Italy

  • F Barbaro

    2   Digestive Endoscopy, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy, Rome, Italy

  • V Pontecorvi

    2   Digestive Endoscopy, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy, Rome, Italy

  • C Spada

    2   Digestive Endoscopy, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy, Rome, Italy

  • I Boskoski

    3   Digestive Endoscopy, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy, Roma, Italy

  • B Vincenzo

    4   Digestive Endoscopy Unit, Fondazione Policlinico Gemelli IRCCS, Rome, Italy, Rome, Italy
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Aims The increasing prevalence of obesity among the young population poses a significant health challenge that necessitates urgent, comprehensive, and sustained interventions. Addressing obesity early in life can mitigate its long-term health impacts and reduce the burden on healthcare systems globally. This study aims to evaluate the role of Endoscopic Sleeve Gastroplasty (ESG) as an effective weight management strategy for adolescents with obesity.

Methods This retrospective analysis of a prospective dataset aimed to assess the impact of weight loss on the quality of life of obese patients aged 18-21 years who underwent ESG. All participants had failed to achieve significant weight loss despite dietary interventions, behavioral modifications, and/or physical activity. Each patient underwent a multidisciplinary evaluation and was scheduled for an ESG procedure. Quality of life was assessed using the BAROS score system [1] and reported at 1-, 3-, 6-, 12- and 24-months follow-up (FU). Weight loss outcomes [Total Body Weight Loss (%TBWL) and Body Mass Index Loss (BMIL)] at each time-point were also recorded.

Results A total of 809 patients underwent ESG at our tertiary center between 2015 and 2024. Among them, 23 individuals (19 women, 82.6%) met the inclusion criteria and underwent ESG between April 2019 and July 2024 (mean age: 19.78±1.24, mean BMI: 36.63±2.43 kg/m²). At the 24-month follow-up (FU rate: 26%) we observed a mean BAROS score of 4±1.08 and a significant BMI reduction of 7.62±2.98 points from baseline with a mean TBWL of 20.58±8.43%. No serious adverse events were collected.

Conclusions Endoscopic Sleeve Gastroplasty offers a unique combination of safety, efficacy, and flexibility, making it an ideal option for young people struggling with obesity. By providing significant weight loss with minimal invasiveness and preserving future treatment options, ESG should be considered as the preferred alternative to bariatric surgery in the adolescent population.



Publikationsverlauf

Artikel online veröffentlicht:
27. März 2025

© 2025. European Society of Gastrointestinal Endoscopy. All rights reserved.

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  • References

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