Endoscopy 2025; 57(S 02): S445
DOI: 10.1055/s-0045-1806142
Abstracts | ESGE Days 2025
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Occurrence of leiomyoma after endoscopic full-thickness resection: a case report

D Orlando
1   Digestive Endoscopy Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy
,
M Coppola
1   Digestive Endoscopy Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy
,
M Casadio
1   Digestive Endoscopy Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy
,
M Coccia
2   Azienda ospedaliero – universitaria Sant'Andrea, Rome, Italy
,
C Moriconi
3   Istituti fisioterapici Ospitalieri, Pathology Departement, Rome, Italy
,
V Stigliano
1   Digestive Endoscopy Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy
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A 73-years old man underwent full thickness endoscopic resection (FTR) for a non polypoid lesion (JNET 2b at narrow band imaging, NBI) with non lifting sign in the transverse colon. The procedure was technically successfull with no complications. Histopathological evaluation described a high-grade dysplasia tubulovillous adenoma with negative margins (R0 resection). After 12 months a surveilleance colonscopy was performed. We reported a peduncolated lesion proximal to the site of the previous resection, with a short stalk and 10 mm head. At NBI examination a small adenomatous area was detected (JNET 2a), despite normal pattern in the remaining surface. The lesions was then resected with hot snare polypectomy. Histology showed a 2 mm area of tubular low grade displasia in the mucosal layer, and a mesenchimal lesion in the submucosa. At immunohistochemical assays the lesion resulted suggestive for submucosal leiomyoma (CD117, claudine, S100 negative, and smooth muscle positive) [1] [2] [3].

This kind of clip artifact was previous described at 12- months colonoscopy follow up after FTR with the endoscopic clip still in site. It is possible that a foreign body could lead to an abnormal growth of the muscularis mucosae.

This eventuality should be kept in mind in order to correctly identify and manage this kind of artifacts and to properly transmit informations to pathologist and patients.



Publication History

Article published online:
27 March 2025

© 2025. European Society of Gastrointestinal Endoscopy. All rights reserved.

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